IL-12p80, Human Recombinant

Products_type

Recombinant Protein
Products_short_name

[IL-12p80]
Products_name_syn

[NKSF; CTL maturation factor (TCMF); Cytotoxic lymphocyte maturation factor (CLMF); TSF; Edodekin-alpha; IL-12.]
Other_names

[interleukin-12 subunit beta; Interleukin-12 subunit beta; interleukin-12 subunit beta; interleukin 12B; Cytotoxic lymphocyte maturation factor 40 kDa subunit; CLMF p40; IL-12 subunit p40; NK cell stimulatory factor chain 2; NKSF2]
Products_gene_name

[IL12B]
Other_gene_names

[IL12B; IL12B; CLMF; NKSF; CLMF2; IMD28; IMD29; NKSF2; IL-12B; NKSF2; IL-12B; CLMF p40; NKSF2]
Purity

>=95%
Form

Sterile filtered through a 0.2 micron filter. Lyophilized from 10 mM Sodium Acetate - pH 5.6, 90 mM NaCl, 2% Sucrose and 4.0% Mannitol.Appearance: Lyophilized powder
Storage_stability

At -20 degree CShelf Life: 12 months
Tested_application

SDS-PAGE; HPLC
Properties

Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
Source

Recombinants or rec. proteins
Group

recombinants

Gene target

IL-12p80
Gene symbol

IL36G, IL25, IL22, IL18, IL37, IL6R, IL17C, IL17D, IL17A, IL23A
Short name

IL-12p80, Recombinant
Technique

Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. MyBioSource advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
Host

(BTI-Tn-5B1-4) Hi-5 Insect Cells
Species

Human, Humans
Alternative name

Interleukin-12p80, H. sapiens Rec.
Alternative technique

rec

Identity

HGNC:6019
Gene

IL6R
Long gene name

interleukin 6 receptor
Synonyms
- CD126
- IL-6R
- IL-1Ra
- IL6RA
- gp80
Synonyms name
- membrane glycoprotein 80
- interleukin 6 receptor subunit alpha
GenBank acession
- X12830
Locus

1q21.3
Discovery year

2001-06-22
Entrez gene record

3570
Pubmed identfication
- 8428753
- 12633863
RefSeq identity
- NM_000565
Classification
- CD molecules
- Interleukin receptors
- Immunoglobulin like domain containing
VEGA ID

OTTHUMG00000036073

Identity

HGNC:5981
Gene

IL17A
Long gene name

interleukin 17A
Synonyms gene
- CTLA8
- IL17
Synonyms gene name
- interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8)
Synonyms
- IL-17A
- IL-17
Synonyms name
- cytotoxic T-lymphocyte-associated protein 8
GenBank acession
- U32659
Locus

6p12.2
Discovery year

1993-10-25
Entrez gene record

3605
Pubmed identfication
- 8390535
RefSeq identity
- NM_002190
Classification
- Interleukins
VEGA ID

OTTHUMG00000014840
Locus Specific Databases
- LRG_1223

Name

Primary Cell Culture
Concept

Scope note: The initial culturing of cells derived directly from fresh TISSUES.
Tree numbers
- E01.370.225.500.223.500
- E05.200.500.265.500
- E05.242.223.500
- E05.481.500.249.500
Qualifiers

ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data