IL-31 Antibody
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Catalog numberbs-10070R
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PricePlease ask
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Size0.1ml
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Long nameIL-31 Primary Polyclonal Antibody
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Also known asIL-31 PAb
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CategoryPrimary Antibodies
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ConjugationUnconjugated
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Target AntigenIL-31
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SpecificityThis is a highly specific antibody against IL-31.
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Modification sNone
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Modification site sUnmodified antibody
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ClonalityPolyclonal antibody
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Clone numberPolyclonal antibody
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Concentration1ug per 1ul
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SourceKLH conjugated synthetic peptide derived from mouse IL-31
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Gene ID number76399
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Tested ApplicationsWB, IHC-P, IF(IHC-P)
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Recommended dilutionsWB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
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Cross reactivityMouse, Rat
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Cross reactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
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Background of the target antigenInterleukin-31 (IL-31) is a recently discovered T-cell cytokine closely related to IL-6 type cytokines and is preferentially produced by T helper type 2 cells. IL-31 activity is mediated through the ligand-induced oligomerization of a dimeric receptor complex containing IL-31 receptor A and oncostatin M receptor. In response to IL-31 binding, these proteins activate the JAK/STAT and the AKT signaling pathways. RNA levels of IL-31 receptor A and oncostatin M receptor are induced in activated monocytes but are expressed constitutively in epithelial cells. IL-31, when overexpressed in transgenic mice, results in the development of pruritis, alopecia and skin lesions, and in humans may result in atopic dermatitis, suggesting that IL-31 may represent a novel target for antipruritic drug development.
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Purification methodThis antibody was purified via Protein A.
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Storage conditionsKeep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
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Synonym namesInterleukin-31; 1700013B14RIK, IL31; interleukin-31 precursor.
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PropertiesIf you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolIL31, SNORD115-31, SNORD114-31, IGKV3-31, ERVK-31, IGLV3-31, RNVU1-31, IGKV3D-31, OR1D5, IL36G
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Short nameAnti-IL-31
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TechniqueAntibody, antibodies against human proteins, antibodies for
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HostRabbit (Oryctolagus cuniculus)
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IsotypeImmunoglobulin G (IgG)
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Alternative nameIL-31 Polyclonal Antibody
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Alternative techniqueantibodies
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Gene info
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Identity
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Gene
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Long gene nameinterleukin 31
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Synonyms
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GenBank acession
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Locus
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Discovery year2003-11-06
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Interleukins
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namesmall nucleolar RNA, C/D box 115-31
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Synonyms
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GenBank acession
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Locus
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Discovery year2007-02-15
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Small nucleolar RNAs, C/D box
Gene info
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Identity
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Gene
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Long gene namesmall nucleolar RNA, C/D box 114-31
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Synonyms
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Locus
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Discovery year2006-09-26
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Small nucleolar RNAs, C/D box
Gene info
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Identity
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Gene
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Long gene nameimmunoglobulin kappa variable 3-31 (pseudogene)
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Synonyms gene name
- immunoglobulin kappa variable 3-31
- immunoglobulin kappa variable 3-31 pseudogene
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GenBank acession
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Locus
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Discovery year2000-04-18
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Entrez gene record
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RefSeq identity
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Classification
- Immunoglobulin kappa locus at 2p11.2
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameendogenous retrovirus group K member 31
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Synonyms gene name
- endogenous retrovirus group K, member 31
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GenBank acession
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Locus
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Discovery year2015-05-14
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Pubmed identfication
Gene info
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Identity
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Gene
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Long gene nameimmunoglobulin lambda variable 3-31 (pseudogene)
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Synonyms gene name
- immunoglobulin lambda variable 3-31
- immunoglobulin lambda variable 3-31 pseudogene
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GenBank acession
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Locus
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Discovery year2000-05-08
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Entrez gene record
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RefSeq identity
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Classification
- Immunoglobulin lambda locus at 22q11.2
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameRNA, variant U1 small nuclear 31
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Locus
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Discovery year2019-07-25
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Classification
- Variant U1 small nuclear RNAs
Gene info
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Identity
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Gene
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Long gene nameimmunoglobulin kappa variable 3D-31 (pseudogene)
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Synonyms gene name
- immunoglobulin kappa variable 3D-31
- immunoglobulin kappa variable 3D-31 pseudogene
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GenBank acession
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Locus
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Discovery year2000-04-18
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Entrez gene record
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RefSeq identity
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Classification
- Immunoglobulin kappa locus at 2p11.2
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameolfactory receptor family 1 subfamily D member 5
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Synonyms gene name
- olfactory receptor, family 1, subfamily D, member 5
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Synonyms
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GenBank acession
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Locus
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Discovery year1998-09-14
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Olfactory receptors, family 1
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameinterleukin 36 gamma
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Synonyms gene
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Synonyms gene name
- interleukin 1 family, member 9
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2002-08-02
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Interleukins
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data