IKZF1 Polyclonal Antibody

• Catalog number
  CAC07645
• Price
  Please ask
• Size
  100 μg

• Other name
  DNA-binding protein Ikaros,Ikaros family zinc finger protein 1,Lymphoid transcription factor LyF-1,IKZF1,IK1,IKAROS,LYF1,ZNFN1A1
• Immunogen
  Recombinant human DNA-binding protein Ikaros protein (1-265AA)
• Verified reactivity
  Human
• Verified applications
  ELISA,WB,IHC,IF. Recommended dilution:WB:1:2000-1:5000,IHC:1:20-1:200,IF:1:50-1:200
• Raised in
  Rabbit
• Clonality
  Polyclonal
• Protein number
  Q13422
• Gene number
  Please refer to GenBank
• NCBI number
  Please refer to NCBI
• Purity
  Protein G purified, >95%
• Storage recommendation
  Aliquot and store at -20°C. Minimize freezing and thawing.
• Use before
  1 year
• Shipping requirements
  Blue ice
• Estimated production time
  3-7 business days
• Supplementary information
  Transcription regulator of hematopoietic cell differentiation (PubMed:17934067). Binds gamma-satellite DNA (PubMed:17135265, PubMed:19141594). Plays a role in the development of lymphocytes, B- and T-cells. Binds and activates the enhancer (delta-A element) of the CD3-delta gene. Repressor of the TDT (fikzfterminal deoxynucleotidyltransferase) gene during thymocyte differentiation. Regulates transcription through association with both HDAC-dependent and HDAC-independent complexes. Targets the 2 chromatin-remodeling complexes, NuRD and BAF (SWI/SNF), in a single complex (PYR complex), to the beta-globin locus in adult erythrocytes. Increases normal apoptosis in adult erythroid cells. Confers early temporal competence to retinal progenitor cells (RPCs) (By similarity). Function is isoform-specific and is modulated by dominant-negative inactive isoforms (PubMed:17135265, PubMed:17934067).
• Notes
  For research use only. Not for diagnostic procedures.
• Hyperlink
• Properties
  If you buy Antibodies supplied by bioma they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Group
  Polyclonals and antibodies
• About
  Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.
• French translation
  anticorps

• Gene target
  IKZF1  
• Gene symbol
  IKZF1
• Short name
  IKZF1 Polyclonal Antibody
• Technique
  Polyclonal, Antibody, antibodies against human proteins, antibodies for, Polyclonal antibodies (pAbs) are mostly rabbit or goat antibodies that are secreted by different B cells, whereas monoclonal antibodies come from a single N cell lineage. Pabs are a collection of immunoglobulin molecules that react against a specific antigen, each identifying a different epitope.
• Label
  Unconjugated
• Alternative name
  IKAROS family zinc finger 1 (Ikaros) polyclonal (antibody to-)
• Alternative technique
  polyclonals, antibodies
• Alternative to gene target
  IKAROS family zinc finger 1 (Ikaros), Hs.54452 and IK1 and IKAROS and LyF-1 and LYF1 and PPP1R92 and PRO0758 and ZNFN1A1, IKZF1 and IDBG-16397 and ENSG00000185811 and 10320, protein heterodimerization activity, nuclei, Ikzf1 and IDBG-150234 and ENSMUSG00000018654 and 22778, BT.93003 and IDBG-628786 and ENSBTAG00000014016 and 541154

Gene info

• Identity
  HGNC:13176
• Gene
  IKZF1
• Long gene name
  IKAROS family zinc finger 1
• Synonyms gene
  • ZNFN1A1
• Synonyms gene name
  • zinc finger protein, subfamily 1A, 1 (Ikaros)
  • IKAROS family zinc finger 1 (Ikaros)
• Synonyms
  • hIk-1
  • LyF-1
  • Hs.54452
  • IKAROS
  • PPP1R92
• Synonyms name
  • protein phosphatase 1, regulatory subunit 92
• GenBank acession
  • U40462
• Locus
  7p12.2
• Discovery year
  1999-08-23
• Entrez gene record
  10320
• Pubmed identfication
  • 1439790
  • 7935426
• RefSeq identity
  • NM_006060
• Classification
  • Zinc fingers C2H2-type
  • Protein phosphatase 1 regulatory subunits
• VEGA ID
  OTTHUMG00000155907
• Locus Specific Databases
  • LRG_1121

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

Similar products