IKK alpha (Tyr463) Antibody, Cy7 Conjugated
-
Catalog numberbs-3234R-Cy7
-
PricePlease ask
-
Size0.1ml
-
-
Long nameIKK alpha (Tyr463) Polyclonal Antibody, Cy7 Conjugated
-
CategoryConjugated Primary Antibodies
-
ConjugationCy7
-
Host OrganismRabbit (Oryctolagus cuniculus)
-
Target AntigenIKK alpha Tyr463
-
SpecificityThis is a highly specific antibody against IKK alpha Tyr463.
-
ModificationPhosphorylation
-
Modification siteTyr463
-
ClonalityPolyclonal
-
ClonePolyclonal antibody
-
Concentration1ug per 1ul
-
SourceKLH conjugated synthetic phosphopeptide derived from human IKK alpha around the phosphorylation site of Tyr463
-
Gene ID number1147
-
Tested applicationsIF(IHC-P)
-
Recommended dilutionsIF(IHC-P)(1:50-200)
-
CrossreactivityHuman, Mouse, Rat
-
Crossreactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
-
Antigen backgroundNuclear factor kappa B (NFkB) is a ubiquitous transcription factor and an essential mediator of gene expression during activation of immune and inflammatory responses. NFkB mediates the expression of a great variety of genes in response to extracellular stimuli including IL1, TNF alpha, and bacterial product LPS. NFkB is associated with IkB proteins in the cell cytoplasm, which inhibit NFkB activity. IKK is a serine protein kinase, and the IKK complex contains alpha and beta subunits (IKK alpha and IKK beta). IKK alpha and IKK beta interact with each other and both are essential for NFkB activation. IKK alpha specifically phosphorylates IkBa. IKKa is expressed in variety of human tissues.
-
Purification methodThis antibody was purified via Protein A.
-
Storage conditionsKeep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
-
Excitation Emission743nm/767nm
-
SynonymsI Kappa B Kinase Alpha; IKKalpha; IKK alpha; IkappaB kinase; IkB kinase alpha subunit; IKBKA; IKK 1; IKK A; IKK a kinase; IKK1; IKKA; Inhibitor Of Kappa Light Polypeptide Gene Enhancer In B Cells; Inhibitor Of Nuclear Factor Kappa B Kinase Alpha Subunit; NFKBIKA; Nuclear Factor Kappa B Inhibitor Kinase Alpha; Nuclear factor NF kappa B inhibitor kinase alpha; Nuclear factor NFkappaB inhibitor kinase alpha; Nuclear Factor Of Kappa Light Chain Gene Enhancer In B Cells Inhibitor; TCF16; CHUK1; Conserved Helix Loop Helix Ubiquitous Kinase; Conserved helix loop ubiquitous kinase; I Kappa B Kinase 1; IKKA_HUMAN.
-
DescriptionThe Anti-IKK alpha Tyr463 is a α- or alpha protein sometimes glycoprotein present in blood.
-
PropertiesIf you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
-
ConjugatedThese antibodies are excite for emission at 650 nm and detected at a 676 nm wavelengths.
-
Additional conjugationCy7
-
French translationanticorps
-
Gene target
-
Gene symbolIKBKE, IKBKB, CHUK, IKBKG
-
Short nameAnti-IKK alpha Tyr463
-
TechniqueAntibody, antibodies against human proteins, antibodies for, antibody Conjugates
-
IsotypeImmunoglobulin G (IgG)
-
LabelCy7
-
Alternative nameAnti-IKK alpha Tyr463 PAb Cy7
-
Alternative techniqueantibodies
-
Gene info
-
Identity
-
Gene
-
Long gene nameinhibitor of nuclear factor kappa B kinase subunit epsilon
-
Synonyms gene name
- inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
-
Synonyms
-
GenBank acession
-
Locus
-
Discovery year2002-12-02
-
Entrez gene record
-
Pubmed identfication
-
Classification
- I kappa B kinases
- MicroRNA protein coding host genes
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene nameinhibitor of nuclear factor kappa B kinase subunit beta
-
Synonyms gene name
- inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
-
Synonyms
-
GenBank acession
-
Locus
-
Discovery year1998-02-11
-
Entrez gene record
-
Pubmed identfication
-
Classification
- I kappa B kinases
- IKK complex
-
VEGA ID
-
Locus Specific Databases
Gene info
-
Identity
-
Gene
-
Long gene namecomponent of inhibitor of nuclear factor kappa B kinase complex
-
Synonyms gene
-
Synonyms gene name
- conserved helix-loop-helix ubiquitous kinase
-
Synonyms
-
Synonyms name
-
GenBank acession
-
Locus
-
Discovery year1995-03-15
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- I kappa B kinases
- IKK complex
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene nameinhibitor of nuclear factor kappa B kinase regulatory subunit gamma
-
Synonyms gene
-
Synonyms gene name
- incontinentia pigmenti
- inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
- inhibitor of nuclear factor kappa B kinase subunit gamma
-
Synonyms
-
Synonyms name
-
GenBank acession
-
Locus
-
Discovery year1998-09-30
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- Zinc fingers C2HC-type
- IKK complex
-
VEGA ID
-
Locus Specific Databases
MeSH Data
-
Name
-
ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
-
Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
-
Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
