IHH Antibody (Indian Hedgehog)
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Catalog number
R31349
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Price
Please ask
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Size
0.1mg
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Category
Antibody
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Concentration
0.5mg/ml if reconstituted with 0.2ml sterile DI water
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Form
Antigen affinity purified
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Conjugation
Unconjugated
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Clone
Polyclonal antibody
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Recognised antigen
IHH (Indian Hedgehog)
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Host animal
Rabbit (Oryctolagus cuniculus)
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Clonality
Polyclonal (rabbit origin)
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Species reactivity
Human (Homo sapiens), Mouse (Mus musculus), Rat ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
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Tested applications
WB
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Recommended dilutions
Western blot: 0.5-1ug/ml
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Notes
The stated application concentrations are suggested starting amounts. Titration of the IHH antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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Intented use
This IHH antibodyis to be used only for research purposes and not for diagnostics..
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Uniprot
Q14623
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Purity
Antigen affinity
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Description
Indian hedgehog, also known as IHH or HHG2 is a protein which in humans is encoded by the IHH gene. This gene encodes a member of the hedgehog family of secreted signaling molecules. Hedgehog proteins are essential regulators of a variety of developmental processes including growth, patterning and morphogenesis. The encoded protein specifically plays a role in bone growth a differentiation. Mutations in this gene are the cause of brachydactyly type A1 which is characterized by shortening or malformation of the phalanges. Mutations in this gene are also the cause of acrocapitofemoral dysplasia.
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Immunogen
An amino acid sequence from the C-terminus of human Indian Hedgehog (EPHRLRAFQVIETQD) was used as the immunogen for this IHH antibody.
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Storage
After reconstitution, the IHH antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized. Avoid repeated freezing and thawing.
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Properties
If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translation
anticorps
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Gene target
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Gene symbol
IHH
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Short name
Anti-IHH (Indian Hedgehog)
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Technique
Antibody, antibodies against human proteins, antibodies for
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Isotype
Rabbit IgG
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Alternative name
Antibodies to IHH (Indian Hedgehog)
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Alternative technique
antibodies
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Alternative to gene target
Indian hedgehog, BDA1 and HHG2, IHH and IDBG-81274 and ENSG00000163501 and 3549, peptidase activity, Extracellular, Ihh and IDBG-169082 and ENSMUSG00000006538 and 16147, BT.22104 and IDBG-643926 and ENSBTAG00000008452 and 522714
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Gene info
MeSH Data
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Name
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Concept
Scope note:
Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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