IgE, Heavy Chain (FITC)

• Catalog number
  GEN609201
• Price
  Please ask
• Size
  500ug

• Also known as
  IgE, Heavy Chain
• Other names
  N/A
• Category
  Antibodies
• Subcategory
  Mnoclonal antibodies
• Gene name
  N/A
• Gene name synonims
  N/A
• Other gene names
  N/A
• Clonality
  Monoclonal
• Immunoglobulin isotype
  IgG1
• Clone
  3H2284
• Host organism
  Rat (Rattus norvegicus)
• Source organism
  Mouse (Mus musculus)
• Species reactivity
  Mouse (Mus musculus); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
• Specificity and cross reactivity
  Recognizes mouse IgE. Does not crossreact with other immunoglobulin classes or subclasses. Does not crossreact with rat IgE.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
• Purification method
  Affinity Purified by affinity chromatography.
• Form Appearance
  Supplied as a liquid in PBS, 0.09% sodium azide, 50% glycerol. Labeled with fluorescein isothiocyanate (FITC).
• Concentration
  N/A
• Storage and shipping
  Store the antibody at +4 degrees Celsius for short term storage.. Aliquot to avoid repeated freezing and thawing. For optimal long term storage, the antibody should be kept at -20 degrees Celsius. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. FITC conjugates are sensitive to light.
• Tested applications
  Flow Cytometry (FC/FACS)
• Properties
  This MBS Monoclonals Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS. When excited at 488 nanometers, FITC has a green emission that's usually collected at 530 nanometers, the FL1 detector of a FACSCalibur or FACScan. FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light. For fluorescent microscopy applications, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept. MBS Monoclonals FITC is highly sensitive to pH extremes. Immunoglobulin E (IgE) kappa or Fc specific antibody is a kind of antibody (or immunoglobulin (Ig) "isotype") that has only been found in mammals. IgE is synthesized by plasma cells. Monomers of IgE consist of two heavy chains (ε chain) and two light chains, with the ε chain containing 4 Ig-like constant domains (Cε1-Cε4). IgEs play a role in allergy and response to parasite infection. High levels of IgEs caused by parasites can lower the allergic reaction of patients to allergens common present in the human environment. As such the parasite history of an allergic patient needs to be taken in consideration as a positive factor.
• Conjugation
  Anti-FITC Antibody

• Gene target
  Heavy   Chain  
• Gene symbol
  CLTC, MYH13, FTHL18P
• Short name
  IgE, Heavy Chain (FITC)
• Technique
  FITC, IgE, Fluorescein, IgEs
• Isotype
  IgE, IgE
• Label
  FITC
• Alternative name
  Anti-IgE, Heavy Chain (FITC)
• Alternative technique
  fluorescine, immunoglobulin-e

Gene info

• Identity
  HGNC:2092
• Gene
  CLTC
• Long gene name
  clathrin heavy chain
• Synonyms gene
  • CLTCL2
• Synonyms gene name
  • clathrin, heavy polypeptide (Hc)
  • clathrin, heavy chain
  • clathrin, heavy polypeptide-like 2
  • clathrin, heavy chain (Hc)
• Synonyms
  • Hc
• GenBank acession
  • X55878
• Locus
  17q23.1
• Discovery year
  1990-10-16
• Entrez gene record
  1213
• Pubmed identfication
  • 1765375
  • 7584026
• RefSeq identity
  • NM_004859
• Classification
  • Clathrin subunits
• VEGA ID
  OTTHUMG00000134279

Gene info

• Identity
  HGNC:7571
• Gene
  MYH13
• Long gene name
  myosin heavy chain 13
• Synonyms gene name
  • myosin, heavy polypeptide 13, skeletal muscle
• Synonyms
  • MyHC-eo
• Synonyms name
  • extraocular muscle myosin heavy chain
  • extraocular myosin heavy chain
• GenBank acession
  • AF075248
• Locus
  17p13.1
• Discovery year
  1998-12-09
• Entrez gene record
  8735
• Pubmed identfication
  • 9806854
• RefSeq identity
  • NM_003802
• Classification
  • Myosin heavy chains, class II
• VEGA ID
  OTTHUMG00000177987

Gene info

• Identity
  HGNC:3988
• Gene
  FTHL18P
• Long gene name
  ferritin heavy chain like 18, pseudogene
• Synonyms gene
  • FTH1P18
  • FTHL18
• Synonyms gene name
  • ferritin, heavy polypeptide-like 18
  • ferritin, heavy polypeptide 1 pseudogene 18
  • ferritin heavy chain 1 pseudogene 18
  • ferritin heavy chain like 18
• GenBank acession
  • AA383232
• Locus
  Xp21.1
• Discovery year
  2000-05-31
• Entrez gene record
  441490
• RefSeq identity
  • NR_171164
• VEGA ID
  OTTHUMG00000033090

MeSH Data

• Name
  Fluorescent Antibody Technique
• Concept
  Scope note: Test for tissue antigen using either a direct method, by conjugation of antibody with fluorescent dye (FLUORESCENT ANTIBODY TECHNIQUE, DIRECT) or an indirect method, by formation of antigen-antibody complex which is then labeled with fluorescein-conjugated anti-immunoglobulin antibody (FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT). The tissue is then examined by fluorescence microscopy.
• Tree numbers
  • E01.370.225.500.607.512.240
  • E01.370.225.750.551.512.240
  • E05.200.500.607.512.240
  • E05.200.750.551.512.240
  • E05.478.583.375
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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