IDO Pathway inhibitor

  • Catalog number
    2746-50
  • Price
    Please ask
  • Size
    50 mg
  • Alternative_name
    1-Methyl-D-tryptophan; Indoximod
  • Description
    IDO pathway inhibitor is a methylated tryptophan with anti-immunosuppressive activity. 1-Methyl-D-tryptophan inhibits the enzyme indoleamine 2,3-dioxygenase (IDO), which degrades the essential amino acid tryptophan, and may increase or maintain tryptophan levels important to T cell function.
  • CAS Number
    110117-83-4
  • Structure Available
    Y
  • Salt Form
    No
  • Molecular Formula
    C₁₂H₁₄N₂O₂
  • Molecular Weight
    218.25
  • Cell Permeable
    Yes
  • Purity
    ≥95%
  • Solubilities
    DMSO
  • Handling
    Protect from air and light
  • Tag Line
    An IDO pathway inhibitor
  • Storage Condition
    -20°C
  • Shipping Condition
    Gel Pack
  • Shelf Life
    36 months
  • MDL Number
    MFCD00274271
  • PubChem CID
    405012
  • SMILES
    CN1C=C(C2=CC=CC=C21)CC(C(=O)O)N
  • InChi
    InChI=1S/C12H14N2O2/c1-14-7-8(6-10(13)12(15)16)9-4-2-3-5-11(9)14/h2-5,7,10H,6,13H2,1H3,(H,15,16)/t10-/m1/s1
  • InChi Key
    ZADWXFSZEAPBJS-SNVBAGLBSA-N
  • MSDS Available
    Yes
  • Additional description
    Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme.
  • Gene target
    IDO   Pathway   inhibitor  
  • Gene symbol
    IDO1
  • Short name
    IDO Pathway inhibitor
  • Alternative name
    Indoleamine 2,3-dioxygenase 1 Pathway suppressor
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