IDH1 Antibody

• Catalog number
  bs-9634R
• Price
  Please ask
• Size
  0.1ml

• Long name
  IDH1 Primary Polyclonal Antibody
• Also known as
  IDH1 PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  IDH1
• Specificity
  This is a highly specific antibody against IDH1.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human IDH1/Isocitrate dehydrogenase
• Gene ID number
  3417
• Tested Applications
  WB, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  The Isocitrate dehydrogenase cytoplasmic enzyme is a homodimer of 416 residues that belongs to the isocitrate and isopropylmalate dehydrogenases family. IDHC catalyzes the third step of the citric acid cycle, which involves the oxidative decarboxylation of isocitrate, forming ?ketoglutarate and CO2 in a two step reaction. The first step involves the oxidation of isocitrate to the intermediate oxalosuccinate, while the second step involves the production of ?ketoglutarate. During this process, either NADH or NADPH is produced along with CO2. Ca2+ can bind to IDHC as a complex with isocitrate, acting as a competitive inhibitor of Mg2+. The IDHC enzyme is inactivated by phosphorylation at Ser-113 and contains a clasp-like domain wherein both polypeptide chains in the dimer interlock. IDHC is expressed in a wide range of species and also in organisms that lack a complete citric acid cycle.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  Cytosolic NADP isocitrate dehydrogenase; Cytosolic NADP-isocitrate dehydrogenase; ICDH; IDCD; IDH; IDHC; Idh1; IDHC_HUMAN; IDP; IDPC; Isocitrate dehydrogenase [NADP] cytoplasmic; Isocitrate dehydrogenase 1 NADP+ soluble; NADP dependent isocitrate dehydrogenase cytosolic; NADP dependent isocitrate dehydrogenase peroxisomal; NADP+-specic ICDH; Oxalosuccinate decarboxylase; PICD.
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  IDH1  
• Gene symbol
  IDH1, IDH1-AS1
• Short name
  Anti-IDH1
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  IDH1 Polyclonal Antibody
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:5382
• Gene
  IDH1
• Long gene name
  isocitrate dehydrogenase (NADP(+)) 1
• Synonyms gene name
  • isocitrate dehydrogenase 1 (NADP+), soluble
  • isocitrate dehydrogenase 1 (NADP+)
  • isocitrate dehydrogenase (NADP(+)) 1, cytosolic
• Locus
  2q34
• Discovery year
  2001-06-22
• Entrez gene record
  3417
• RefSeq identity
  • NM_005896
• Classification
  • Isocitrate dehydrogenases
• VEGA ID
  OTTHUMG00000132943
• Locus Specific Databases
  • LRG_610

Gene info

• Identity
  HGNC:40292
• Gene
  IDH1-AS1
• Long gene name
  IDH1 antisense RNA 1
• Synonyms gene name
  • IDH1 antisense RNA 1 (non-protein coding)
• GenBank acession
  • AI492612
  • BE465811
• Locus
  2q34
• Discovery year
  2012-02-24
• Entrez gene record
  100507475
• Classification
  • Antisense RNAs
• VEGA ID
  OTTHUMG00000154707

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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