ICOS/CD278 Antibody, ALEXA FLUOR 350
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Catalog number
bs-2583R-A350
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Price
Please ask
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Size
100ul
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Long name
ICOS/CD278 Polyclonal Antibody, ALEXA FLUOR 350 Conjugated
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Also known as
Anti-ICOS/CD278 PAb ALEXA FLUOR 350
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Category
Conjugated Primary Antibodies
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Conjugated with
ALEXA FLUOR® 350
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Host Organism
Rabbit (Oryctolagus cuniculus)
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Target Antigen
ICOS/CD278
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Specificity
This is a highly specific antibody against ICOS/CD278.
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Modification
Unmodified
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Modification Site
None
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Clonality
Polyclonal
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Clone
Polyclonal antibody
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Concentration
1ug per 1ul
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Immunogen range
40-90/199
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Subcellular location
Extracellular
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Source
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human ICOS
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Gene ID Number
29851
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Swiss Prot
Q9Y6W8
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Tested applications
IF(IHC-P)
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Recommended dilutions
IF(IHC-P)(1:50-200)
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Crossreactivity
Human, Mouse, Rat
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Cross reactive species details
Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
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Background of the antigen
Enhances all basic T-cell responses to a foreign antigen, namely proliferation, secretion of lymphokines, up-regulation of molecules that mediate cell-cell interaction, and effective help for antibody secretion by B-cells. Essential both for efficient interaction between T and B-cells and for normal antibody responses to T-cell dependent antigens. Does not up-regulate the production of interleukin-2, but superinduces the synthesis of interleukin-10. Prevents the apoptosis of pre-activated T-cells. Plays a critical role in CD40-mediated class switching of immunoglobin isotypes (By similarity).
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Purification
Purified by Protein A.
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Storage conditions
Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
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Excitation emission
343nm/442nm
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Synonyms
AILIM; CD278; CVID1; Inducible T-cell costimulator; Activation-inducible lymphocyte immunomediatory molecule; ICOS
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Properties
For facs or microscopy Alexa 1 conjugate. Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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Conjugation
Alexa Fluor, ALEXA FLUOR 350
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French translation
anticorps
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Gene target
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Gene symbol
ICOS, ICOSLG
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Short name
Anti-ICOS/CD278
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Technique
Antibody, antibodies against human proteins, antibodies for
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Isotype
Immunoglobulin G (IgG)
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Label
ALEXA FLUOR 350
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Alternative name
ICOS/CD278 Polyclonal Antibody, ALEXA FLUOR 350
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Alternative technique
antibodies
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Alternative to gene target
inducible T-cell co-stimulator, ICOS and IDBG-79246 and ENSG00000163600 and 29851, protein binding, Extracellular, Icos and IDBG-159737 and ENSMUSG00000026009 and 54167, ICOS and IDBG-643378 and ENSBTAG00000021596 and 507026
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Gene info
Gene info
MeSH Data
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Name
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Concept
Scope note:
Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
Product images
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