WNT-3a, Human Recombinant
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Catalog number
P1194-100
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Price
Please ask
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Size
100 ug
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Synonyms
Protein Wnt-3a, WNT3A
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Alternative_names
Protein Wnt-3a, WNT3A
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Description
Plays a key role in oncogenesis and embryogenesis
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Recombinant
Yes
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Source
E.coli
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Purity by SDS PAGE
> 85%
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Assay
SDS-PAGE
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Molecular Weight
37.5 kDa
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Storage Temp
-20°C
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Shipping
Gel Pack
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Shelf Life
12 months
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Appearance
Liquid
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Physical form description
In 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol
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Background Information
The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. WNT3a is a member of the WNT gene family. It encodes a protein which shows 96% amino acid identity to mouse Wnt3A protein, and 84% to human WNT3 protein, another WNT gene product. This protein is clustered with WNT14 gene, another family member, in chromosome 1q42 region. Recombinant human WNT3a protein was expressed in E.coli
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Amino acid sequence
MSYPIWWSLA VGPQYSSLGS QPILCASIPG LVPKQLRFCR NYVEIMPSVA EGIKIGIQEC QHQFRGRRWN CTTVHDSLAI FGPVLDKATR ESAFVHAIAS AGVAFAVTRS CAEGTAAICG CSSRHQGSPG KGWKWGGCSE DIEFGGMVSR EFADARENRP DARSAMNRHN NEAGRQAIAS HMHLKCKCHG LSGSCEVKTC WWSQPDFRAI GDFLKDKYDS ASEMVVEKHR ESRGWVETLR PRYTYFKVPT ERDLVYYEAS PNFCEPNPET GSFGTRDRTC NVSSHGIDGC DLLCCGRGHN ARAERRREKC RCVFHWCCYV SCQECTRVYD VHTCK
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Handling
Centrifuge the vial prior to opening.
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Usage
For Research Use Only! Not to be used in humans
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Properties
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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Additional source
Recombinants or rec. proteins
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Group
recombinants
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Gene target
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Gene symbol
WNT7A, WNT4, WNT10B
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Short name
WNT-3a, Recombinant
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Technique
Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Biovision advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
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Species
Human, Humans
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Alternative name
WNT-3a, H. sapiens Rec.
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Alternative technique
rec
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Gene info
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Identity
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Gene
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Long gene name
Wnt family member 7A
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Synonyms gene name
- wingless-type MMTV integration site family, member 7A
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year
1996-03-12
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
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VEGA ID
Gene info
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Identity
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Gene
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Long gene name
Wnt family member 4
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Synonyms gene name
- wingless-type MMTV integration site family, member 4
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Synonyms
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GenBank acession
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Locus
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Discovery year
2000-07-31
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Entrez gene record
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Pubmed identfication
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Classification
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VEGA ID
Gene info
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Identity
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Gene
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Long gene name
Wnt family member 10B
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Synonyms gene name
- wingless-type MMTV integration site family, member 10B
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Synonyms
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GenBank acession
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Locus
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Discovery year
1997-09-05
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
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VEGA ID
MeSH Data
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Name
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Concept
Scope note:
The initial culturing of cells derived directly from fresh TISSUES.
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Tree numbers
- E01.370.225.500.223.500
- E05.200.500.265.500
- E05.242.223.500
- E05.481.500.249.500
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
Product images
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