Human Recombinant Ubiquitin K29R

Human Recombinant Ubiquitin K29R is available 2 times from Biovision labs

6406-500 | Human Recombinant Ubiquitin-K29Rsize: 500 μg | 184.4 USD

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6406-1000 | Human Recombinant Ubiquitin-K29Rsize: 1 mg | 267.27 USD

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  • Background
    Ubiquitin is a small polypeptide that can be conjugated via its C-terminus to amine groups of lysine residue on target proteins. This conjunction is referred to as monoubiquitylation. Additional ubiquitin moieties can be subsequently conjugated to this initial ubiquitin, utilizing any one of the seven lysine residues on the surface of ubiquitin. The formation of these ubiquitin chains is referred to as polyubiquitylation. This tag-free recombinant form of human ubiquitin is engineered to have a single substitution of arginine for lysine at position 29. Covalent attachment of ubiquitin to other proteins serves various functions, but its major role is to target cellular proteins for destruction. Cellular components that activate, transfer, remove, or simply recognize ubiquitin number in the hundreds, perhaps even in the thousands. In light of this complexity the ubiquitin pathway is ideal for a systems biology approach. Ubiquitin plays a very important role in regulated non-lysosomal ATP dependent protein degradation. The Ub-proteasome proteolytic pathway, which is a complex process, is implicated to be of great importance for regulating numerous cellular processes.
  • Concentration
    4 mg/ml
  • Molecular weight
    8.592 kDa
  • Synonym
    Human Recombinant Ubiquitin-K29R
  • NCBI gene number
    6233
  • NCBI gene
    RPS27A
  • Gene source
    Human
  • NCBI number
    P62979
  • Recombinant
    Yes
  • Source
    E. Coli
  • Purification
    ≥95%
  • Tested applications
    RP-HPLC, N/A
  • Level of endotoxin
    N/A
  • Tested activity
    N/A
  • Biological activity
    N/A
  • Reesults
    N/A
  • Binding ability
    N/A
  • Unit
    N/A
  • Storage condition
    -80°C
  • Shipping under
    gel pack
  • Physical appearance
    Liquid
  • Physical properties
    4 mg/ml in 20 mM Tris, pH 7.5, 0.15 M NaCl and 10% glycerol.
  • How to reconstitute
    N/A
  • Aa sequence
    N/A
  • Before use
    Centrifuge the vial prior to opening.
  • Notes
    For Research Use Only! Not to be used in humans
  • Properties
    Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
  • Additional source
    Recombinants or rec. proteins
  • Group
    recombinants
  • Gene target
  • Short name
    Recombinant Ubiquitin-K29R
  • Technique
    Recombinant
  • Species
    Human
  • Alternative name
    H. sapiens recombinant Ubiquitin-K29R
  • Alternative technique
    rec
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