Human Recombinant PPIL1

• Catalog number
  6317-100
• Price
  Please ask
• Size
  100 ug

• Synonyms
  Human Recombinant PPIL1
• Alternative_names
  Peptidylprolyl isomerase (cyclophilin)-like 1, Rotamase, CGI-124, CYPL1, hCyPX, PPIase.
• Description
  An immunophilin family protein catalyzing the isomerization of peptide bonds
• Recombinant
  Yes
• Source
  E. coli
• Purity by SDS PAGE
  ≥95%
• Assay
  SDS-PAGE
• Biological activity
  Specific activity is > 300 nmoles/min/mg.
• Unit Definition
  Specific activity is defined as the amount of enzyme that cleaves 1 µmole of Suc-AAFP-pNA per minute at 25°C in Tris-HCl pH 8.0 using chymotrypsin.
• Molecular Weight
  19.3 kDa
• Storage Temp
  -20°C
• Shipping
  gel pack
• Shelf Life
  12 months
• Concentration
  1 mg/ml
• Appearance
  Liquid
• Physical form description
  1 mg/ml solution in 20 mM Tris-HCl buffer (pH 8.0) containing 20% glycerol.
• Background Information
  Peptidylprolyl isomerase (cyclophilin)-like 1, also known as PPIL1, is a member of peptidyl-propyl cis trans isomerase (PPIase) family, which catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerates the folding of proteins. Human PPIL1 might play an important role in proliferation of cancer cells through modulation of phosphorylation of stathmin. So it can be developed as a novel molecular target for colon-cancer therapy.
• Amino acid sequence
  MAAIPPDSWQ PPNVYLETSM GIIVLELYWK HAPKTCKNFA ELARRGYYNG TKFHRIIKDF MIQGGDPTGT GRGGASIYGK QFEDELHPDL KFTGAGILAM ANAGPDTNGS QFFVTLAPTQ WLDGKHTIFG RVCQGIGMVN RVGMVETNSQ DRPVDDVKII KAYPSGLEHH HHHH
• Handling
  Centrifuge the vial prior to opening.
• Usage
  For Research Use Only! Not to be used in humans
• Datasheet
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Additional source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  PPIL1  
• Gene symbol
  PPIL1
• Short name
  Recombinant PPIL1
• Technique
  Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Biovision advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Species
  Human, Humans
• Alternative name
  H. sapiens Rec. PPIL1
• Alternative technique
  rec

Gene info

• Identity
  HGNC:9260
• Gene
  PPIL1
• Long gene name
  peptidylprolyl isomerase like 1
• Synonyms gene name
  • peptidylprolyl isomerase (cyclophilin)-like 1
• Synonyms
  • CYPL1
• Synonyms name
  • cyclophilin like 1
• GenBank acession
  • AF090992
• Locus
  6p21.2
• Discovery year
  1995-09-05
• Entrez gene record
  51645
• Pubmed identfication
  • 10072585
  • 8978786
• Classification
  • Cyclophilin peptidylprolyl isomerases
  • Spliceosomal C complex
  • Spliceosomal B complex
  • Spliceosomal Bact complex
  • Spliceosomal P complex
• VEGA ID
  OTTHUMG00000014612

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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