Recombinant Human Microphthalmia-associated transcription factor (MITF)
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Catalog number
MBS1236019
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Price
Please ask
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Size
0.02 mg (E-Coli)
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Products_type
Recombinant Protein
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Products_short_name
[Microphthalmia-associated transcription factor (MITF)]
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Other_names
[microphthalmia-associated transcription factor isoform 4; Microphthalmia-associated transcription factor; microphthalmia-associated transcription factor; melanogenesis associated transcription factor; Class E basic helix-loop-helix protein 32; bHLHe32]
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Products_gene_name
[MITF]
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Other_gene_names
[MITF; MITF; MI; WS2; CMM8; WS2A; COMMAD; bHLHe32; BHLHE32; bHLHe32]
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Purity
>85% (SDS-PAGE)
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Form
Lyophilized or liquid (Format to be determined during the manufacturing process)
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Storage_stability
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
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Description
Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells. The activation of transcription factor subunits is the first step of gene expression, in which a particular segment of DNA is copied into RNA (mRNA) by the enzyme RNA polymerases. Transcription factors, unites and elongations can be RNA and DNA nucleic acids, base pairs of nucleotides . Converting from DNA to RNA is made by enzymatic reactions. During transcription, a DNA sequence is read by an RNA polymerase, which produces a complementary, anti-parallel RNA strand called a primary transcript. Transcriptions are key functions in signal transduction pathways. Signaling ligand binding transcription factors play an important role in transduction cascades.
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Properties
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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Source
Recombinants or rec. proteins
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Group
recombinants
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Gene target
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Gene symbol
MITF
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Short name
Recombinant Microphthalmia-associated transcription factor (MITF)
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Technique
Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. MyBioSource advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
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Host
E Coli or Yeast or Baculovirus or Mammalian Cell
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Species
Human, Humans
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Alternative name
Rec. H. sapiens Microphthalmia-associated transcription factor (microphthalmia-associated transcription factor)
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Alternative technique
rec
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Alternative to gene target
microphthalmia-associated transcription factor, bHLHe32 and CMM8 and MI and WS2 and WS2A, MITF and IDBG-44086 and ENSG00000187098 and 4286, protein dimerization activity, nuclei, Mitf and IDBG-172461 and ENSMUSG00000035158 and 17342, BT.29882 and IDBG-644985 and ENSBTAG00000006679 and 407219
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Gene info
MeSH Data
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Name
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Concept
Scope note:
The initial culturing of cells derived directly from fresh TISSUES.
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Tree numbers
- E01.370.225.500.223.500
- E05.200.500.265.500
- E05.242.223.500
- E05.481.500.249.500
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
Product images
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