human IL7 Antibody
human IL7 Antibody is available 1 time from Boster labs
- Target antigenhuman IL7
- ClonalityPolyclonal antibody
- ClonePolyclonal antibody
- Raised inrabbit
- Type of the antibodyIgG polyclonal antibody
- Product formfreeze-dried
- Reacts with species:human
- ImmunogenE. coli-derived human IL-7 recombinant protein(Position: D26-H177).
- Product configurationEach vial contains 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
- PurificationImmunogen affinity purified.
- SolubilizationThe powdered antibody should be dissolved in 0.2 ml of distilled water to achieve final concentration of 500ug/ml
- Storage condtionsKeep the human IL7 Antibodyat minus twenty degrees Celsius for 1 year. The ready-to-use solutions can be stored at four degrees Celsius for a month. Our specialsits recommend to freeze the aliquotes at minus twenty degrees Celsius for long-term application. Multiple procedures of freezing and thawing influence the specifity and reactivity of the antibody in a negative way.
- TipsThe human IL7 Antibody did not cross-reacted with other proteins during the test procedures. This antobdy is intended to be used for research analyses and it is not applicale for in vitro diagnostics.
- BackgroundInterleukin 7 (IL-7) is a protein that in humans is encoded by the IL7 gene. The protein encoded by this gene is a cytokine important for B and T cell development. This cytokine and the hepatocyte growth factor (HGF) form a heterodimer that functions as a pre-pro-B cell growth-stimulating factor. And it is found to be a cofactor for V(D)J rearrangement of the T cell receptor beta (TCRB) during early T cell development. In addition, this cytokine can be produced locally by intestinal epithelial and epithelial goblet cells, and may serve as a regulatory factor for intestinal mucosal lymphocytes. Knockout studies in mice suggested that this cytokine plays an essential role in lymphoid cell survival. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional splice variants have been described but their presence in normal tissues has not been confirmed.
- Related articles1. Goodwin RG, Lupton S, Schmierer A, Hjerrild KJ, Jerzy R, Clevenger W, Gillis S, Cosman D, Namen AE (January 1989). "Human interleukin 7: molecular cloning and growth factor activity on human and murine B-lineage cells". Proc. Natl. Acad. Sci. U.S.A. 86 (1): 302–6. 2. Lupton SD, Gimpel S, Jerzy R, et al. (1990). "Characterization of the human and murine IL-7 genes". J. Immunol. 144 (9): 3592–601. 3. Sutherland GR, Baker E, Fernandez KE, Callen DF, Goodwin RG, Lupton S, Namen AE, Shannon MF, Vadas MA (July 1989). "The gene for human interleukin 7 (IL7) is at 8q12-13". Hum. Genet. 82 (4): 371–2.
- Gene NameIL7
- Protein NameInterleukin-7(IL-7)
- Gene Full Nameinterleukin 7
- SynonymsIL 7 antibody|IL-7 antibody|Il7 antibody|Interleukin 7 antibody|Interleukin-7 antibody
- Uniprot IDP13232
- PropertiesIf you buy Antibodies supplied by boster they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
- GeneIL-7 is a hematopoietic growth factor secreted by stromal cells in the bone marrow and thymus. It is also produced by keratinocytes, dendritic cells, hepatocytes, neurons, and epithelial cells but is not produced by normal lymphocytes. Recombinant, rec. E. coli interleukin-7 for cell culture or antibody production.
- French translationanticorps
- Gene target
- Short nameIL7 Antibody
- Alternative nameH. sapiens interleukin 7 (Antibody to)
- Alternative techniqueantibodies
- Alternative to gene targetinterleukin 7, IL-7, IL7 and IDBG-26153 and ENSG00000104432 and 3574, this GO :0002360 and T cell lineage commitment and biological process this GO :0005125 and cytokine activity and molecular function this GO :0005126 and cytokine receptor binding and molecular function this GO :0005139 and interleukin-7 receptor binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005615 and extracellular space and cellular component this GO :0006955 and immune response and biological process this GO :0006959 and humoral immune response and biological process this GO :0007267 and cell-cell signaling and biological process this GO :0008083 and growth factor activity and molecular function this GO :0008284 and positive regulation of cell proliferation and biological process this GO :0009887 and organ morphogenesis and biological process this GO :0010468 and regulation of gene expression and biological process this GO :0030890 and positive regulation of B cell proliferation and biological process this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0043086 and negative regulation of catalytic activity and biological process this GO :0045453 and bone resorption and biological process this GO :0045582 and positive regulation of T cell differentiation and biological process this GO :0046622 and positive regulation of organ growth and biological process this GO :0048873 and homeostasis of number of cells within a tissue and biological process this GO :2001237 and negative regulation of extrinsic apoptotic signaling pathway and biological process this GO :2001240 and negative regulation of extrinsic apoptotic signaling pathway in absence of ligand and biological process, growth factor activity, this GO :0005125: cytokine activity and also this GO :0005126: cytokine receptor binding and also this GO :0005139: interleukin-7 receptor binding and also this GO :0005515: protein binding and also this GO :0008083: growth factor activity, this GO :0005125: cytokine activity, this GO :0005126: cytokine receptor binding, this GO :0005139: interleukin-7 receptor binding, this GO :0005515: protein binding, this GO :0008083: growth factor activity, Extracellular, Il7 and IDBG-130583 and ENSMUSG00000040329 and 16196, IL7 and IDBG-644827 and ENSBTAG00000016284 and 280827
RP1013 | human IL7 Antibodysize: 0,1 mg | 460.36 USD