Fibrinogen alpha chain Antibody, ALEXA FLUOR 555

  • Catalog number
    bs-7548R-A555
  • Price
    Please ask
  • Size
    100ul
  • Long name
    Fibrinogen alpha chain Antibody, ALEXA FLUOR 555 Conjugated
  • Also known as
    Anti-Fibrinogen alpha chain PAb ALEXA FLUOR 555
  • Category
    Conjugated Primary Antibodies
  • Conjugated with
    ALEXA FLUOR® 555
  • Host Organism
    Rabbit (Oryctolagus cuniculus)
  • Target Antigen
    Fibrinogen alpha chain
  • Specificity
    This is a highly specific antibody against Fibrinogen alpha chain.
  • Modification
    Unmodified
  • Modification Site
    None
  • Clonality
    Polyclonal
  • Clone
    Polyclonal antibody
  • Concentration
    1ug per 1ul
  • Immunogen range
    70-105/866
  • Subcellular location
    Secreted
  • Source
    This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Fibrinogen alpha chain
  • Gene ID Number
    2243
  • Swiss Prot
    P02671
  • Tested applications
    IF(IHC-P)
  • Recommended dilutions
    IF(IHC-P)(1:50-200)
  • Crossreactivity
    Human, Mouse, Rat
  • Cross reactive species details
    Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
  • Background of the antigen
    Cleaved by the protease thrombin to yield monomers which, together with fibrinogen beta (FGB) and fibrinogen gamma (FGG), polymerize to form an insoluble fibrin matrix. Fibrin has a major function in hemostasis as one of the primary components of blood clots. In addition, functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re-epithelialization. Was originally thought to be essential for platelet aggregation, based on in vitro studies using anticoagulated blood. However, subsequent studies have shown that it is not absolutely required for thrombus formation in vivo. Enhances expression of SELP in activated platelets via an ITGB3-dependent pathway. Maternal fibrinogen is essential for successful pregnancy. Fibrin deposition is also associated with infection, where it protects against IFNG-mediated hemorrhage. May also facilitate the immune response via both innate and T-cell mediated pathways.
  • Purification
    Purified by Protein A.
  • Storage conditions
    Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
  • Excitation emission
    553nm/568nm
  • Synonyms
    Fib2; Fibrinogen alpha chain; FGA
  • Properties
    For facs or microscopy Alexa 1 conjugate. Very high photo stable ALEXA conjugate. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
  • Conjugation
    Alexa Fluor, ALEXA FLUOR 555
  • Description
    The Anti-Fibrinogen alpha chain is a α- or alpha protein sometimes glycoprotein present in blood.
  • French translation
    anticorps
  • Gene target
  • Gene symbol
    FGA
  • Short name
    Anti-Fibrinogen alpha chain
  • Technique
    Antibody, antibodies against human proteins, antibodies for
  • Isotype
    Immunoglobulin G (IgG)
  • Label
    ALEXA FLUOR 555
  • Alternative name
    Fibrinogen alpha chain Antibody, ALEXA FLUOR 555
  • Alternative technique
    antibodies
Gene info
  • Identity
  • Gene
    FGA
  • Long gene name
    fibrinogen alpha chain
  • Synonyms gene name
    • fibrinogen, A alpha polypeptide
  • Locus
  • Discovery year
    2001-06-22
  • Entrez gene record
  • RefSeq identity
  • Classification
    • Fibrinogen C domain containing
    • Receptor ligands
  • VEGA ID
  • Locus Specific Databases
MeSH Data
  • Name
  • Concept
    Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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