Human DR6 (TNFRSF21)/Fc Chimera

Type

Recombinant protein
Expression system

HEK 293 cell line
Description

Human DR6 (Death Receptor-6; TNFRSF21) is a type I transmembrane protein containing cytoplasmic death domain, member of the TNF receptor superfamily, expressed in most human tissues. The extracellular domain of human DR6 (aa 1 - 212) is fused to the Fc portion of human IgG1
Format

Lyophilized powder
Purity

> 95% determined by SDS-PAGE
Purification methd

Purified from cell culture supernatant via protein-A affinity chromatography
Shipping and storage

Store lyophilized product in freezer (-20 °C to -80 °C). The expiration date of unopened product vial is indicated on the vial label. After reconstitution prepare suitable aliquots. Reconstituted product is stable for at least 6 months when stored in freezer (-20 °C to -80 °C). Avoid freeze/thaw cycles.
Datasheet
Properties

Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.

Gene target

DR6 TNFRSF21
Gene symbol

TNFRSF21
Short name

DR6 (TNFRSF21)/Fc
Technique

FC, Fc chimeras and Chimera RNAi's are part non target species constructions.
Species

Human, Humans
Alternative name

Recombinant human DR6 (TNFRSF21)/Fc Chimera
Alternative to gene target

tumor necrosis factor receptor superfamily, member 21, TNFRSF21 and IDBG-90063 and ENSG00000146072 and 27242, protein binding, Plasma membranes, Tnfrsf21 and IDBG-184035 and ENSMUSG00000023915 and 94185, TNFRSF21 and IDBG-632394 and ENSBTAG00000020054 and 537922