Human CellExp TIM 4 human recombinant

Human CellExp TIM 4 human recombinant is available 2 times from Biovision labs

P1108-50 | Human CellExp™ TIM-4, human recombinantsize: 50 µg | 534.24 USD

Ajax processing

P1108-10 | Human CellExp™ TIM-4, human recombinantsize: 10 μg | 174.28 USD

Ajax processing
  • Target
    TIMD4
  • Background
    The TIM (T cell/transmembrane, immunoglobulin and mucin) family plays a critical role in regulating immune responses, including allergy, asthma, transplant tolerance, autoimmunity and the response to viral infections. The unique structure of TIM immunoglobulin variable region domains allows highly specific recognition of phosphatidylserine (PtdSer), exposed on the surface of apoptotic cells. TIM-4 (T cell; immunoglobulin; Mucin-4), also known as SMUCKLER, is a 60 kDa member of the TIM family of immune regulating proteins. TIM-4 is exclusively expressed on antigen-presenting cells, where it mediates phagocytosis of apoptotic cells and plays an important role in maintaining tolerance. TIM-4 binds specifically to TIM-1 which is also the cellular receptor for the hepatitis A virus, and has been implicated in the development of asthma. Among hematopoietic cells, TIM-1 is expressed on activated B and T cells, preferentially in the Th2 subset of CD4+ T cells. The interaction of TIM-4 with TIM-1 induces costimulatory and hyperproliferative signals in T cells.
  • Concentration
    N/A
  • Synonym
    TIM4; TIMD4, T Cell Immunoglobulin and Mucin Domain-containing Protein 4, T Cell Membrane Protein 4
  • Other name
    TIM4, TIMD4, T Cell Immunoglobulin and Mucin Domain-containing Protein 4, T Cell Membrane Protein 4
  • NCBI gene number
    91937
  • NCBI gene
    TIMD4
  • Gene source
    Human
  • NCBI number
    Q96H15
  • Recombinant
    Yes
  • Source
    CHO cells
  • Purification
    ≥98%
  • Tested applications
    SDS-PAGE, N/A
  • Level of endotoxin
    < 0.06 EU/μg
  • Tested activity
    Measured by its ability to inhibit anti-CD3-induced proliferation of stimulated human T cells.
  • Biological activity
    Measured by its ability to inhibit anti-CD3-induced proliferation of stimulated human T cells.
  • Reesults
    N/A
  • Binding ability
    N/A
  • Unit
    N/A
  • Storage condition
    -20°C
  • Shipping under
    Gel pack
  • Physical appearance
    Lyophilized
  • Physical properties
    Lyophilized from 0.2 μm-filtered solution in PBS
  • How to reconstitute
    Reconstitute with 100 µl sterile water.
  • Aa sequence
    N/A
  • Before use
    Centrifuge the vial prior to opening.
  • Notes
    For Research Use Only! Not to be used in humans
  • Properties
    Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
  • Additional source
    Recombinants or rec. proteins
  • Group
    recombinants
  • Gene target
  • Short name
    CellExp™ TIM-4, recombinant
  • Technique
    Recombinant
  • Species
    Humans
  • Alternative name
    H. sapiens CellExp™ TIM-4, H. sapiens recombinant
  • Alternative technique
    rec
Simillar products
Supplier:EnoGene
Price:336.03USD
Supplier:trca
Price:239.21USD
Supplier:trca
Price:387.29USD
Supplier:MBS Monoclonals
Price:435.14USD
Supplier:ABM microrna
Price:2 478.68USD
Supplier:MyBioSource
Price:0.00USD
Supplier:MyBioSource
Price:378.18USD
Supplier:MyBioSource
Price:0.00USD
Supplier:SFC
Price:0.00USD
Supplier:MBS Recombinant
Price:1 812.31USD
Supplier:MBS Recombinant
Price:1 718.90USD
Supplier:bioma
Price:967.10USD
Supplier:SFC
Price:0.00USD
Supplier:MyBioSource
Price:378.18USD
Supplier:abm Adinovirus
Price:750.67USD
Supplier:Biomatik
Price:364.51USD
Supplier:MyBioSource
Price:0.00USD
Filters
+32-(0)1-658-90-45 lieven@gentaur.com
Human CellExp TIM 4 human recombinant - Gentaur.com
Contact
Chat with gentaur.com employee