Human CellExp ErbB3 HER3 human recombinant

Human CellExp ErbB3 HER3 human recombinant is available 1 time from Biovision labs

7400-10 | Human CellExp ErbB3/HER3, human recombinantsize: 10 μg | 388.05 USD

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  • Synonyms
    ERBB3, ErbB-3, HER3, HER-3, LCCS2, MDA-BF-1, MGC88033, c-erbB-3, c-erbB3, erbB3-S, p180-ErbB3, p45-sErbB3, p85-sErbB3, Receptor tyrosine-protein kinase erbB-3
  • Alternates names
    ERBB3, ErbB-3, HER3, HER-3, LCCS2, MDA-BF-1, MGC88033, c-erbB-3, c-erbB3, erbB3-S, p180-ErbB3, p45-sErbB3, p85-sErbB3, Receptor tyrosine-protein kinase erbB-3
  • Taglines
    Involved in pathways leading to cell proliferation or differentiation.
  • Biomolecule/Target
    ErbB3
  • NCBI Gene ID #.
    2065
  • NCBI Gene Symbol
    ErbB3
  • Gene Source
    Human
  • Accession #
    P21860
  • Recombinant
    Yes
  • Source
    HEK293 cells
  • Purity
    N/A
  • Activity (Specifications/test method)
    N/A
  • Biological activity
    Measured by its ability to inhibit the biological activity of Neuregulin1-β1 on MCF-7 human breast cancer cells, in the presence of 10 ng/ml recombinant Human NRG1-β1/HRG1-β1 Extracellular Domain. The ED50 for this effect is typically 0.5-3.0 μg/ml
  • Results
    Measured by its ability to inhibit the biological activity of Neuregulin1-β1 on MCF-7 human breast cancer cells, in the presence of 10 ng/ml recombinant Human NRG1-β1/HRG1-β1 Extracellular Domain. The ED50 for this effect is typically 0.5-3.0 μg/ml
  • Molecular Weight
    This protein is fused with a C-terminal 6×his tag and has a calculated MW of 71.5 kDa after removal of signal peptide. The predicted N-terminal is Ser 20. Protein migrates as 100-110 kDa in reduced SDS-PAGE resulting from glycosylation.
  • Storage Temp.
    -20°C
  • Shipping
    Gel Pack
  • Shelf Life
    1 year
  • Concentration
    N/A
  • Appearance
    Lyophilized
  • Physical form description
    Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Generally 5-8% Mannitol or trehalose is added as a protectant before lyophilization.
  • Reconstitution Instructions
    Centrifuge the vial prior to opening. Reconstitute in sterile PBS, pH 7.4 to a concentration of 50 µg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 month. For extended storage, it is recommended to store at -20°C.
  • Handling
    Centrifuge the vial prior to opening.
  • Usage
    For Research Use Only! Not to be used in humans
  • Properties
    Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
  • Additional source
    Recombinants or rec. proteins
  • Group
    recombinants
  • Gene target
  • Short name
    CellExp ErbB3/HER3, recombinant
  • Technique
    Recombinant
  • Species
    Human
  • Alternative name
    H. sapiens CellExp v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)/HER3, H. sapiens recombinant
  • Alternative technique
    rec
  • Alternative to gene target
    v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian), c-erbB-3 and c-erbB3 and ErbB-3 and erbB3-S and HER3 and LCCS2 and MDA-BF-1 and p180-ErbB3 and p45-sErbB3 and p85-sErbB3, ERBB3 and IDBG-39824 and ENSG00000065361 and 2065, transferase activity, Extracellular, Erbb3 and IDBG-197943 and ENSMUSG00000018166 and 13867, ERBB3 and IDBG-636302 and ENSBTAG00000010444 and 785655
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