Human CellExp EPOR Erythropoietin Receptor human recombinant
Human CellExp EPOR Erythropoietin Receptor human recombinant is available 2 times from Biovision labs
- SynonymsEPOR, Erythropoietin Receptor.
- Alternates namesEPOR, Erythropoietin Receptor.
- TaglinesA major glycoprotein hormone regulator of mammalian erythropoiesis
- Biomolecule/TargetEPOR/Erythropoietin Receptor
- NCBI Gene ID #.2057
- NCBI Gene SymbolEPOR
- Gene SourceHuman
- Accession #P19235
- SourceHEK293 cells
- Activity (Specifications/test method)N/A
- Biological activityMeasured by its ability to inhibit Epo-dependent proliferation of TF‑1 human erythroleukemic cells. The ED50 for this effect is typically 2 - 6 ng/ml in the presence of 0.2 U/ml of rhEpo-Fc.
- ResultsMeasured by its ability to inhibit Epo-dependent proliferation of TF‑1 human erythroleukemic cells. The ED50 for this effect is typically 2 - 6 ng/ml in the presence of 0.2 U/ml of rhEpo-Fc.
- Molecular WeightThis protein is fused with Fc fragment of human IgG1 at the C-terminus, has a calculated MW of 50.1 kDa. The predicted N-terminus is Ala 25. DTT-reduced Protein migrates as 55-60 kDa due to glycosylation.
- Storage Temp.-20°C
- ShippingGel Pack
- Shelf Life1 year
- Physical form descriptionLyophilized from 0.22 μm filtered solution in 50 mM tris, 100 mM glycine, pH 7.0. Normally Mannitol or Trehalose is added as protectants before lyophilization.
- Reconstitution InstructionsCentrifuge the vial prior to opening. Reconstitute in sterile PBS, pH 7.4 to a concentration of 50 µg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 month. For extended storage, it is recommended to store at -20°C.
- HandlingCentrifuge the vial prior to opening.
- UsageFor Research Use Only! Not to be used in humans
- PropertiesHuman proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
- DescriptionThe receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
- Additional sourceRecombinants or rec. proteins
- Gene target
- Short nameCellExp™ EPOR/Erythropoietin Receptor, recombinant
- Alternative nameH. sapiens CellExp™ erythropoietin receptor/Erythropoietin Receptor, H. sapiens recombinant
- Alternative techniquerec
- Alternative to gene targeterythropoietin receptor, EPO-R, EPOR and IDBG-29281 and ENSG00000187266 and 2057, identical protein binding, Extracellular, Epor and IDBG-142378 and ENSMUSG00000006235 and 13857, EPOR and IDBG-643528 and ENSBTAG00000008197 and 281144
7454-10 | Human CellExp™ EPOR/Erythropoietin Receptor, human recombinantsize: 10 μg | 385.28 USD
7454-50 | Human CellExp™ EPOR/Erythropoietin Receptor, human recombinantsize: 50 μg | 869.79 USD