Human CellExp™ Collagen II / COL2A1, Human recombinant

• Catalog number
  P1056-50
• Price
  Please ask
• Size
  50 ug

• Synonyms
  COL2A1, Collagen alpha-1(II) chain, Chondrocalcin
• Alternative_names
  COL2A1, Collagen alpha-1(II) chain, Chondrocalcin
• Description
  Promotes normal embryonic development of the skeleton, for linear growth and for the ability of cartilage to resist compressive forces.
• Recombinant
  Yes
• Source
  HEK 293 cells
• Purity by SDS PAGE
  > 95%
• Assay
  SDS-PAGE
• Endotoxin Level
  < 1.0 EU per/ug
• Molecular Weight
  28.2 kDa
• Storage Temp
  -20°C
• Shipping
  Gel Pack
• Shelf Life
  12 months
• Appearance
  Lyophilized
• Reconstitution Instructions
  Reconstitute in sterile PBS, pH 7.4 to a concentration of 50 µg/ml.
• Background Information
  Collagen alpha-1(II) chain (COL2A1) is also known as Alpha-1 type II collagen, which can be cleaved into the following 2 chains: Collagen alpha-1(II) chain and Chondrocalcin. COL2A1 belongs to the fibrillar collagen family. Type II collagen / COL2A1 is specific for cartilaginous tissues. It is essential for the normal embryonic development of the skeleton, for linear growth and for the ability of cartilage to resist compressive forces.
• Handling
  Centrifuge the vial prior to opening.
• Usage
  For Research Use Only! Not to be used in humans
• Datasheet
• Gene
  Collagen Types in bones and muscles can be hydrolyzed and used in human grafts. ( Type II )
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Additional source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  CellExp™   Collagen   COL2A1  
• Gene symbol
  COL2A1
• Short name
  CellExp™ Collagen II / COL2A1, recombinant
• Technique
  Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Biovision advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Species
  Humans
• Alternative name
  H. sapiens CellExp™ Collagen II / collagen, classification II, a 1, H. sapiens Rec.
• Alternative technique
  rec
• Alternative to gene target
  collagen, type II, alpha 1, ANFH and AOM and COL11A3 and SEDC and STL1, COL2A1 and IDBG-29355 and ENSG00000139219 and 1280, platelet-derived growth factor binding, Extracellular, Col2a1 and IDBG-179337 and ENSMUSG00000022483 and 12824, COL2A1 and IDBG-632928 and ENSBTAG00000013155 and 407142

Gene info

• Identity
  HGNC:2200
• Gene
  COL2A1
• Long gene name
  collagen type II alpha 1 chain
• Synonyms gene
  • SEDC
  • AOM
• Synonyms gene name
  • collagen, type II, alpha 1 (primary osteoarthritis, spondyloepiphyseal dysplasia, congenital)
  • arthroophthalmopathy, progressive (Stickler syndrome)
  • collagen, type II, alpha 1
  • collagen type II alpha 1
• Synonyms
  • STL1
• GenBank acession
  • X16468
• Locus
  12q13.11
• Discovery year
  1986-01-01
• Entrez gene record
  1280
• Pubmed identfication
  • 1677770
• RefSeq identity
  • NM_001844
• Classification
  • Collagens
• VEGA ID
  OTTHUMG00000149896
• Locus Specific Databases
  • LOVD - Center for Medical Genetics, Ghent, Belgium

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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