Human CellExp™ CD71 / TFRC / TFR, human recombinant

  • Catalog number
    7279-50
  • Price
    Please ask
  • Size
    50 ug
  • Synonyms
    CD71, TFRC, TFR, sTfR, TfR1, Trfr, T9, p90
  • Alternative_names
    CD71, TFRC, TFR, sTfR, TfR1, Trfr, T9, p90
  • Description
    A protein required for iron delivery from transferrin to cells
  • Recombinant
    Yes
  • Source
    HEK293 cells
  • Purity by SDS PAGE
    ≥92%
  • Assay
    SDS-PAGE
  • Biological activity
    Measured by its binding ability in a functional ELISA. Immobilized rhCD71/TFR at 10 ug/ml (100 ul/well) can bind human Transferrin. The EC50 of human Transferrin is 6.4 ng/ml.
  • Results
    Measured by its binding ability in a functional ELISA. Immobilized rhCD71/TFR at 10 ug/ml (100 ul/well) can bind human Transferrin. The EC50 of human Transferrin is 6.4 ng/ml.
  • Molecular Weight
    This protein is fused with 6×His tag at the N-terminus, has a calculated MW of 76 kDa. The predicted N-terminus is Cys 89. DTT-reduced Protein migrates as 80-85 kDa due to glycosylation.
  • Storage Temp
    -20°C
  • Shipping
    Gel Pack
  • Shelf Life
    12 months
  • Appearance
    Lyophilized
  • Physical form description
    Lyophilized from 0.22 um filtered solution in PBS, pH7.4. Generally 5-8% Mannitol or trehalose is added as a protectant before lyophilization.
  • Reconstitution Instructions
    Centrifuge the vial prior to opening. Reconstitute in sterile PBS, pH 7.4 to a concentration of 50 µg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 month. For extended storage, it is recommended to store at -20°C.
  • Background Information
    CD antigen CD71 is also known as Transferrin receptor protein 1, TfR, sTfR, p90, TfR1, Trfr, which belongs to the peptidase M28 family and M28B subfamily. CD71 /TFR contains one PA (protease associated) domain. CD71 / TfR1 is required for iron delivery from transferrin to cells. CD71 is a potential new target in cases of human leukemia & lymphoma. CD71 /TFRC / TfR has been shown to interact with GABARAP and HFE.
  • Handling
    Centrifuge the vial prior to opening.
  • Usage
    For Research Use Only! Not to be used in humans
  • Properties
    Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
  • Additional source
    Recombinants or rec. proteins
  • Group
    recombinants
  • Gene target
    CellExp™   CD71   TFRC   TFR  
  • Gene symbol
    TFRC
  • Short name
    CellExp™ CD71 / TFRC / TFR, recombinant
  • Technique
    Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Biovision advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
  • Species
    Humans
  • Alternative name
    H. sapiens CellExp™ CD71 / transferrin receptor (p90, CD71) / TFR, H. sapiens Rec.
  • Alternative technique
    rec
  • Alternative to gene target
    transferrin receptor (p90, CD71), CD71 and p90 and T9 and TFR and TFR1 and TR and TRFR, TFRC and IDBG-71016 and ENSG00000072274 and 102724492,7037, poly(A) RNA binding, Extracellular, Tfrc and IDBG-154429 and ENSMUSG00000022797 and 22042, TFRC and IDBG-633841 and ENSBTAG00000032719 and 100852305,504698
Gene info
  • Identity
  • Gene
  • Long gene name
    transferrin receptor
  • Synonyms gene name
    • transferrin receptor (p90, CD71)
  • Synonyms
  • GenBank acession
  • Locus
  • Discovery year
    2001-06-22
  • Entrez gene record
  • Classification
    • M28 metallopeptidases
    • CD molecules
  • VEGA ID
MeSH Data
  • Name
  • Concept
    Scope note: The initial culturing of cells derived directly from fresh TISSUES.
  • Tree numbers
    • E01.370.225.500.223.500
    • E05.200.500.265.500
    • E05.242.223.500
    • E05.481.500.249.500
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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