Human CellExp™ CD68 / SR-D1 Protein, Fc Tag
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Catalog number7880-50
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PricePlease ask
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Size50 ug
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SynonymsCD68, Macrosialin, Gp110, SCARD1, LAMP4
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Alternative_namesCD68, Macrosialin, Gp110, SCARD1, LAMP4
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DescriptionA glycoprotein which binds to low density lipoprotein
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RecombinantYes
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SourceHEK293 cells
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Purity by SDS PAGE>95%
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AssaySDS-PAGE
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Molecular Weight59.2 kDa
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Storage Temp+4°C
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ShippingGel Pack
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Shelf Life12 months
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AppearanceDry powder
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Physical form descriptionLyophilized powder
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Reconstitution InstructionsReconstitute in sterile deionized water to a stock solution of 400 µg/mL. Solubilize for 30 to 60 minutes at room temperature with occasional gentle mixing. Carrier protein (0.1% (W/V) HSA or BSA) is recommended for further dilution and long term storage.
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Background InformationCD antigen CD68 is also known as Macrosialin, Gp110, which belongs to the LAMP family. CD68 / Macrosialin is highly expressed by blood monocytes and tissue macrophages. Also expressed in lymphocytes, fibroblasts and endothelial cells. Expressed in many tumor cell lines which could allow them to attach to selectins on vascular endothelium, facilitating their dissemination to secondary sites. CD68 / Macrosialin could play a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. CD68 / Macrosialin binds to tissue- and organ-specific lectins or selectins, allowing homing of macrophage subsets to particular sites. Rapid recirculation of CD68 from endosomes and lysosomes to the plasma membrane may allow macrophages to crawl over selectin-bearing substrates or other cells.
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Amino acid sequenceAsn 22 - Ser 319
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HandlingCentrifuge the vial prior to opening.
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UsageFor Research Use Only! Not to be used in humans
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PropertiesHuman proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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Gene target
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Gene symbolMSR1, MEGF10, LMOD1, MARCO, SNRPD1, SRPRB, SIGMAR1, SNCG, CD68, CXCL16
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Short nameCellExp™ CD68 / SR-D1 Protein, Fc Tag
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TechniqueFC, Tags
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LabelFc Tag
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SpeciesHumans
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Alternative nameH. sapiens CellExp™ CD68 molecule / SR-D1 Protein, fragment c detection labelled
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Alternative to gene targetCD68 molecule, GP110 and LAMP4 and SCARD1, CD68 and IDBG-25923 and ENSG00000129226 and 968, Plasma membranes, Cd68 and IDBG-191443 and ENSMUSG00000018774 and 12514, CD68 and IDBG-635034 and ENSBTAG00000000133 and 504960
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Gene info
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Identity
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Gene
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Long gene namemacrophage scavenger receptor 1
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Synonyms
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GenBank acession
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Locus
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Discovery year1991-08-07
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Pubmed identfication
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Classification
- CD molecules
- Scavenger receptors
- Scavenger receptor cysteine rich domain containing
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namemultiple EGF like domains 10
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Synonyms gene name
- multiple EGF-like-domains 10
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Synonyms
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GenBank acession
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Locus
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Discovery year2006-03-31
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Scavenger receptors
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameleiomodin 1
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Synonyms gene name
- leiomodin 1 (smooth muscle)
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Synonyms
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GenBank acession
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Locus
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Discovery year2000-03-22
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Entrez gene record
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namemacrophage receptor with collagenous structure
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1998-11-26
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Scavenger receptors
- Scavenger receptor cysteine rich domain containing
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namesmall nuclear ribonucleoprotein D1 polypeptide
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Synonyms gene
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Synonyms gene name
- small nuclear ribonucleoprotein D1 polypeptide (16kD)
- small nuclear ribonucleoprotein D1 polypeptide 16kDa
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Synonyms
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GenBank acession
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Locus
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Discovery year1990-06-13
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Sm spliceosomal proteins
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameSRP receptor subunit beta
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Synonyms gene name
- signal recognition particle receptor, B subunit
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Synonyms
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GenBank acession
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Locus
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Discovery year2004-01-29
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Entrez gene record
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Pubmed identfication
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namesigma non-opioid intracellular receptor 1
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Synonyms gene
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Synonyms gene name
- opioid receptor, sigma 1
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Synonyms
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GenBank acession
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Locus
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Discovery year1993-03-11
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namesynuclein gamma
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1998-04-07
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Entrez gene record
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Pubmed identfication
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene nameCD68 molecule
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Synonyms gene name
- CD68 antigen
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1993-06-11
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Scavenger receptors
- Lysosome associated membrane proteins
- CD molecules
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameC-X-C motif chemokine ligand 16
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Synonyms gene name
- chemokine (C-X-C motif) ligand 16
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2001-09-21
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Chemokine ligands
- Scavenger receptors
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VEGA ID
