Human CellExp™ BTLA, Human recombinant

  • Catalog number
    9228-10
  • Price
    Please ask
  • Size
    10 µg
  • Synonyms
    BTLA, CD272
  • Alternative_names
    BTLA, CD272
  • Description
    B- and T-lymphocyte attenuator
  • Recombinant
    Yes
  • Source
    HEK 293 cells
  • Purity by SDS PAGE
    ≥92%
  • Assay
    SDS-PAGE
  • Purity
    ≥92%
  • Endotoxin Level
    < 1 EU/ug
  • Activity Specifications test method
    Measured by its binding ability in a functional ELISA
  • Biological activity
    Immobilized Human HVEM, C-Twin Strep Tag at 2 ng/ml (100 µl/well),can bind Human BTLA, Fc Tag with a linear of 0.1-0.5 ug/mL.
  • Binding Capacity
    Immobilized Human HVEM, C-Twin Strep Tag at 2 ng/ml (100 µl/well),can bind Human BTLA, Fc Tag with a linear of 0.1-0.5 ug/mL.
  • Molecular Weight
    This protein is fused with a human IgG1 Fc tag at C-terminus and has a calculated MW of 38.7 kDa. The protein migrates as 45-50 kDa in SDS-PAGE due to glycosylation.
  • Storage Temp
    -20°C
  • Shipping
    Gel pack
  • Shelf Life
    12 months
  • Appearance
    Lyophilized
  • Physical form description
    Lyophilized from 0.22 um filtered solution in PBS, pH 7.4. Normally Mannitol or Trehalose is added as protectants before lyophilization.
  • Reconstitution Instructions
    Reconstitute in sterile PBS, pH 7.4 to a concentration of 50 ug/ml
  • Background Information
    B- and T-lymphocyte attenuator (BTLA) is also known as B- and T-lymphocyte-associated protein, CD antigen CD272. BTLA contains one Ig-like V-type (immunoglobulin-like) domain. As a lymphocyte inhibitory receptor, BTLA / CD272 inhibits lymphocytes during immune response. BTLA / CD272 can interact with tyrosine phosphatases PTPN6/SHP-1 and PTPN11/SHP-2, and interact with TNFRSF14/HVEM.
  • Handling
    Centrifuge the vial prior to opening.
  • Usage
    For Research Use Only! Not to be used in humans
  • Properties
    Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
  • Additional source
    Recombinants or rec. proteins
  • Group
    recombinants
  • Gene target
  • Gene symbol
    BTLA
  • Short name
    CellExp™ BTLA, recombinant
  • Technique
    Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Biovision advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
  • Species
    Humans
  • Alternative name
    H. sapiens CellExp™ B and T lymphocyte associated, H. sapiens Rec.
  • Alternative technique
    rec
  • Alternative to gene target
    B and T lymphocyte associated, BTLA and IDBG-49858 and ENSG00000186265 and 151888, protein binding, Cell surfaces, Btla and IDBG-162900 and ENSMUSG00000052013 and 208154, BTLA and IDBG-632288 and ENSBTAG00000011871 and 531767
Gene info
MeSH Data
  • Name
  • Concept
    Scope note: The initial culturing of cells derived directly from fresh TISSUES.
  • Tree numbers
    • E01.370.225.500.223.500
    • E05.200.500.265.500
    • E05.242.223.500
    • E05.481.500.249.500
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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