HtrA2/Omi Antibody, ALEXA FLUOR 594

• Catalog number
  bs-1271R-A594
• Price
  Please ask
• Size
  100ul

• Long name
  HtrA2/Omi Polyclonal Antibody, ALEXA FLUOR 594 Conjugated
• Also known as
  Anti-HtrA2/Omi PAb ALEXA FLUOR 594
• Category
  Conjugated Primary Antibodies
• Conjugated with
  ALEXA FLUOR® 594
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  HtrA2/Omi
• Specificity
  This is a highly specific antibody against HtrA2/Omi.
• Modification
  Unmodified
• Modification Site
  None
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human HtrA2
• Gene ID Number
  27429
• Tested applications
  IF(IHC-P)
• Recommended dilutions
  IF(IHC-P)(1:50-200)
• Crossreactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the antigen
  Serine protease that shows proteolytic activity against a non-specific substrate beta-casein. Promotes or induces cell death either by direct binding to and inhibition of BIRC proteins(also called inhibitor of apoptosis proteins, IAPs), leading to an increase in caspase activity, or by a BIRC inhibition-independent, caspase-independent and serine protease activity-dependent mechanism. Isoform 2 seems to be proteolytically inactive. [CATALYTIC ACTIVITY] Cleavage of non-polar aliphatic amino-acids at the P1 position, with a preference for Val, Ile and Met. At the P2 and P3 positions, Arg is selected most strongly with a secondary preference for other hydrophilic residues. [SUBUNIT] Homotrimer. Interacts with MXI2. The mature protein, but not the precursor, binds to BIRC2, BIRC3 and XIAP.
• Purification
  Purified by Protein A.
• Storage conditions
  Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
• Excitation emission
  590nm/617nm
• Synonyms
  High temperature requirement protein a2; HTRA 2; HtrA like serine protease; HtrA serine peptidase 2; Omi stress regulated endoprotease; PARK 13; PARK13; Protease serine 25; PRSS 25; PRSS25; Serine protease 25; Serine protease HTRA2 mitochondrial; HtrA2; HTRA2_HUMAN; mitochondrial; Omi stress-regulated endoprotease; Serine protease HTRA2; Serine proteinase OMI; Serine protease htra2 mitochondrial precursor; Serine protease omi.
• Properties
  For facs or microscopy Alexa 1 conjugate. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Conjugation
  Alexa Fluor, ALEXA FLUOR® 594
• Conjugated
  Alexa conjugate 1
• French translation
  anticorps

• Gene target
  HtrA2/Omi  
• Gene symbol
  HTRA2
• Short name
  Anti-HtrA2/Omi
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Immunoglobulin G (IgG)
• Label
  ALEXA FLUOR 594
• Alternative name
  HtrA2/Omi Polyclonal Antibody, ALEXA FLUOR 594
• Alternative technique
  antibodies
• Alternative to gene target
  HtrA serine peptidase 2, HTRA2 and IDBG-57753 and ENSG00000115317 and 27429, unfolded protein binding, nuclei, Htra2 and IDBG-159586 and ENSMUSG00000068329 and 64704, HTRA2 and IDBG-631258 and ENSBTAG00000020124 and 523039

Gene info

• Identity
  HGNC:14348
• Gene
  HTRA2
• Long gene name
  HtrA serine peptidase 2
• Synonyms gene
  • PRSS25
• Synonyms gene name
  • protease, serine, 25
• Synonyms
  • OMI
  • PARK13
• Locus
  2p13.1
• Discovery year
  2001-09-26
• Entrez gene record
  27429
• Pubmed identfication
  • 10644717
  • 10971580
• RefSeq identity
  • NM_013247
• Classification
  • PDZ domain containing
  • Serine proteases
• VEGA ID
  OTTHUMG00000129957

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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