Human CellExp™ LAG3 / CD223, Fc Tag, human recombinant

  • Catalog number
    P1149-10
  • Price
    Please ask
  • Size
    10 ug
  • Synonyms
    LAG3, CD223, FDC
  • Alternative_names
    LAG3, CD223, FDC
  • Description
    A protein involved in lymphocyte activation
  • Recombinant
    Yes
  • Source
    HEK 293 cells
  • Purity by SDS PAGE
    > 95%
  • Assay
    SDS-PAGE
  • Endotoxin Level
    < 1.0 EU per/ug
  • Activity Specifications test method
    Measured by its binding ability in a functional ELISA.
  • Biological activity
    Immobilized Human LAG-3, Fc Tag at 2ug/mL (100 uL/well) can bind Anti-LAG3 MAb, Human IgG1 with a linear range of 0.1-2 ng/mL.
  • Binding Capacity
    Immobilized Human LAG-3, Fc Tag at 2ug/mL (100 uL/well) can bind Anti-LAG3 MAb, Human IgG1 with a linear range of 0.1-2 ng/mL.
  • Molecular Weight
    72.3 kDa
  • Storage Temp
    -20°C
  • Shipping
    Gel Pack
  • Shelf Life
    12 months
  • Appearance
    Lyophilized
  • Physical form description
    Lyophilized from 0.22 um filtered solution in PBS, pH7.4. Normally Trehalose is added as protectant before lyophilization.
  • Reconstitution Instructions
    Reconstitute in sterile deionized water to the desired protein concentration.
  • Background Information
    Lymphocyte activation gene 3 protein (LAG3) is also known as CD antigen CD223 and protein FDC, which belongs to immunoglobulin (Ig) superfamily and contains 4 extracellular Ig-like domains. The LAG3 gene contains 8 exons. The sequence data, exon/intron organization, and chromosomal localization all indicate a close relationship of LAG3 to CD4. LAG3 /CD223 involved in lymphocyte activation. LAG3 /CD223 binds to HLA class-II antigens.
  • Handling
    Centrifuge the vial prior to opening.
  • Usage
    For Research Use Only! Not to be used in humans
  • Properties
    Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
  • Additional source
    Recombinants or rec. proteins
  • Group
    recombinants
  • Gene target
    CellExp™   LAG3   CD223   Tag  
  • Gene symbol
    LAG3
  • Short name
    CellExp™ LAG3 / CD223, Fc Tag, recombinant
  • Technique
    Recombinant, FC, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Biovision advises they will be reconstituted in a buffer soluion or culture medium for cell culture. Tags
  • Label
    Fc Tag
  • Species
    Humans
  • Alternative name
    H. sapiens CellExp™ lymphocyte-activation gene 3 / CD223, fragment c detection labelled, H. sapiens Rec.
  • Alternative technique
    rec
  • Alternative to gene target
    lymphocyte-activation gene 3, CD223, LAG3 and IDBG-14994 and ENSG00000089692 and 3902, MHC class II protein binding, Cell surfaces, Lag3 and IDBG-188462 and ENSMUSG00000030124 and 16768, BT.18959 and IDBG-640276 and ENSBTAG00000034295 and 515155
Gene info
  • Identity
  • Gene
  • Long gene name
    lymphocyte activating 3
  • Synonyms gene name
    • lymphocyte-activation gene 3
  • Synonyms
  • Locus
  • Discovery year
    1991-06-03
  • Entrez gene record
  • RefSeq identity
  • Classification
    • Immunoglobulin like domain containing
    • CD molecules
  • VEGA ID
MeSH Data
  • Name
  • Concept
    Scope note: The initial culturing of cells derived directly from fresh TISSUES.
  • Tree numbers
    • E01.370.225.500.223.500
    • E05.200.500.265.500
    • E05.242.223.500
    • E05.481.500.249.500
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
Product images
Similar products
Filters
Contact
Chat with gentaur.com employee