HSPB1 Antibody

• Catalog number
  R30899
• Price
  Please ask
• Size
  0.1mg

• Category
  Antibody
• Concentration
  0.5mg/ml if reconstituted with 0.2ml sterile DI water
• Form
  Antigen affinity purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  HSPB1
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Human (Homo sapiens), Mouse (Mus musculus), Rat ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  WB, IHC-P, IHC-F, ICC
• Recommended dilutions
  Western blot: 0.5-1ug/ml,IHC (Paraffin): 0.5-1ug/ml,IHC (Frozen): 0.5-1ug/ml,Immunocytochemistry: 0.5-1ug/ml
• Notes
  The stated application concentrations are suggested starting amounts. Titration of the HSPB1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
• Intented use
  This HSPB1 antibodyis to be used only for research purposes and not for diagnostics..
• Uniprot
  P04792
• Purity
  Antigen affinity
• Description
  HSPB1 (Heat shock 27kDa protein 1) is a protein that in humans is encoded by the HSPB1 gene. Stock et al.(2003) used FISH to map the HSP27 gene to 7q11.23. The protein encoded by this gene is induced by environmental stress and developmental changes. The encoded protein is involved in stress resistance and actin organization and translocates from the cytoplasm to the nucleus upon stress induction. Defects in this gene are a cause of Charcot-Marie-Tooth disease type 2F (CMT2F) and distal hereditary motor neuropathy (dHMN).
• Immunogen
  An amino acid sequence from the middle region of human HSP27 (KHEERQDEHGYISRCFTR) was used as the immunogen for this HSPB1 antibody (100% homologous in human, mouse and rat).
• Storage
  After reconstitution, the HSPB1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized. Avoid repeated freezing and thawing.
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  HSPB1  
• Gene symbol
  HSPB1
• Short name
  Anti-HSPB1
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit IgG
• Alternative name
  Antibodies to HSPB1
• Alternative technique
  antibodies
• Alternative to gene target
  heat shock 27kDa protein 1, CMT2F and HEL-S-102 and HMN2B and HS.76067 and Hsp25 and HSP27 and HSP28 and SRP27, HSPB1 and IDBG-23058 and ENSG00000106211 and 3315, poly(A) RNA binding, nuclei, Hspb1 and IDBG-204151 and ENSMUSG00000004951 and 15507, HSPB1 and IDBG-640144 and ENSBTAG00000011969 and 516099

Gene info

• Identity
  HGNC:5246
• Gene
  HSPB1
• Long gene name
  heat shock protein family B (small) member 1
• Synonyms gene name
  • heat shock 27kD protein 1
  • heat shock 27kDa protein 1
• Synonyms
  • HSP27
  • HSP28
  • Hs.76067
  • Hsp25
  • CMT2F
• GenBank acession
  • X54079
• Locus
  7q11.23
• Discovery year
  1991-07-09
• Entrez gene record
  3315
• Pubmed identfication
  • 2243808
  • 9344682
• Classification
  • Small heat shock proteins
• VEGA ID
  OTTHUMG00000023228
• Locus Specific Databases
  • Inherited Peripheral Neuropathies Mutation Database
  • LRG_248

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

Similar products