SLAP Antibody, ALEXA FLUOR 647
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Catalog numberbs-13668R-A647
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PricePlease ask
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Size100ul
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Long nameSLAP Polyclonal Antibody, ALEXA FLUOR 647 Conjugated
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Also known asAnti-SLAP PAb ALEXA FLUOR 647
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CategoryConjugated Primary Antibodies
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Conjugated withALEXA FLUOR® 647
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Host OrganismRabbit (Oryctolagus cuniculus)
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Target AntigenSLAP
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SpecificityThis is a highly specific antibody against SLAP.
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ModificationUnmodified
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Modification SiteNone
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ClonalityPolyclonal
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ClonePolyclonal antibody
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Concentration1ug per 1ul
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SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human SLAP
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Tested applicationsIF(IHC-P)
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Recommended dilutionsIF(IHC-P)(1:50-200)
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CrossreactivityHuman, Mouse, Rat
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Cross reactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
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Background of the antigenThe Src homology 3 (SH3) region is a small protein domain of approximately 60 amino acids present in a large group of proteins. In general, it exists in association with catalytic domains, as in the nonreceptor protein-tyrosine kinases and phospholipase C-? within structural proteins, such as spectrin or Myosin; and in small adapter proteins, such as Crk and GRB2. SH3 domains are often accompanied by SH2 domains of 100 amino acids, which bind to tyrosine-phosphorylated regions of target proteins, frequently linking activated growth factors to putative signal transduction proteins. The functions of SH3 domains are not as well defined. Deletion or mutation of SH3 domains generally activate the transforming potential of nonreceptor tyrosine kinases, suggesting that SH3 mediates negative regulation of an intrinsic transforming activity. 3BP1 has been identified as a protein with a high affinity proline-rich binding site for the SH3 domain of c-Abl p120. A similar putative adapter protein, designated Slap, for Src-like adapter protein, has been cloned. Slap contains a single SH2 and SH3 domain that exhibits homology with those from members of the Src kinase family. The N- and C-termini, however, are unique.
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PurificationPurified by Protein A.
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Storage conditionsStore this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
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Excitation emission650nm/665nm
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SynonymshSLAP; SLA 1; SLA; SLA1; SLAP 1; SLAP; SLAP-1; SLAP1; SLAP1_HUMAN; Src like adapter; Src like adapter protein 1; Src like adaptor; SRC-like-adapter; Src-like-adapter protein 1.
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PropertiesFor facs or microscopy Alexa 1 conjugate. Alexa Fluor 633 is a practical alternative to APC as well as Cy5. Bioss Primary Conjugated Antibodies. ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode. It is detected in the FL4 detector of the core's upgraded 2-laser FACScans. Like other Alexa Fluor dyes, the Anti-SLAP exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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ConjugationAlexa Fluor, ALEXA FLUOR 647
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French translationanticorps
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Gene target
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Gene symbolSLA, SLMAP, SLA2, FYB1
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Short nameAnti-SLAP
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TechniqueAntibody, antibodies against human proteins, antibodies for
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IsotypeImmunoglobulin G (IgG)
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LabelALEXA FLUOR 647
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Alternative nameSLAP Polyclonal Antibody, ALEXA FLUOR 647
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Alternative techniqueantibodies
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Gene info
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Identity
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Gene
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Long gene nameSrc like adaptor
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Synonyms gene name
- Src-like-adapter
- Src-like-adaptor
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Synonyms
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Locus
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Discovery year1995-08-11
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Entrez gene record
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Pubmed identfication
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Classification
- SH2 domain containing
- MicroRNA protein coding host genes
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namesarcolemma associated protein
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2001-12-03
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- STRIPAK complex
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameSrc like adaptor 2
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Synonyms gene
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Synonyms gene name
- Src-like-adaptor 2
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Synonyms
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GenBank acession
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Locus
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Discovery year2001-12-19
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- SH2 domain containing
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameFYN binding protein 1
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Synonyms gene
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Synonyms gene name
- FYN-binding protein (FYB-120/130)
- FYN binding protein
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1998-04-22
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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VEGA ID
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Locus Specific Databases
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
