HNF4A, ID (Hepatocyte Nuclear Factor 4-alpha, HNF-4-alpha, Transcription Factor HNF-4, Nuclear Receptor Subfamily 2 Group A Member 1, Transcription Factor 14, HNF4, NR2A1, TCF14)

• Catalog number
  MBS627862
• Price
  Please ask
• Size
  0,2 mL

• Other size
  please contact us to order other different size
• Description
  The HNF4A, ID (Hepatocyte Factor 4-alpha, HNF-4-alpha, Transcription Factor HNF-4, Receptor Subfamily 2 Group A Member 1, Transcription Factor 14, HNF4, NR2A1, TCF14) is a α- or alpha protein sometimes glycoprotein present in blood. Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels. The activation of transcription factor subunits is the first step of gene expression, in which a particular segment of DNA is copied into RNA (mRNA) by the enzyme RNA polymerases. Transcription factors, unites and elongations can be RNA and DNA nucleic acids, base pairs of nucleotides . Converting from DNA to RNA is made by enzymatic reactions. During transcription, a DNA sequence is read by an RNA polymerase, which produces a complementary, anti-parallel RNA strand called a primary transcript. Transcriptions are key functions in signal transduction pathways. Signaling ligand binding transcription factors play an important role in transduction cascades.

• Gene target
  HNF4A   Hepatocyte   Factor   4-alpha   HNF-4-alpha   Transcription   Factor   HNF-4   Receptor   Subfamily   Group   Member   Transcription   Factor   HNF4   NR2A1   TCF14  
• Gene symbol
  HNF4A, ONECUT1, MIR1302-4, PIRC18, PIRC16, SNORD114-4, IGKV2OR2-4, MIR941-4
• Short name
  HNF4A, ID (Hepatocyte Factor 4-alpha, HNF-4-alpha, Transcription Factor HNF-4, Receptor Subfamily 2 Group A Member 1, Transcription Factor 14, HNF4, NR2A1, TCF14)
• Alternative name
  HNF4A, ID (Hepatocyte Nuclear Factor 4-a, HNF-4-a, Transcription Factor HNF-4, Nuclear Receptor Subfamily 2 family A Member 1, Transcription Factor 14, HNF4, NR2A1, TCF14)

Gene info

• Identity
  HGNC:5024
• Gene
  HNF4A
• Long gene name
  hepatocyte nuclear factor 4 alpha
• Synonyms gene
  • TCF14
  • MODY
  • MODY1
• Synonyms
  • NR2A1
  • HNF4
• GenBank acession
  • X76930
• Locus
  20q13.12
• Discovery year
  1998-04-20
• Entrez gene record
  3172
• Pubmed identfication
  • 7926813
  • 9048927
• Classification
  • MicroRNA protein coding host genes
  • Hepatocyte nuclear factor 4 family
• VEGA ID
  OTTHUMG00000032531
• Locus Specific Databases
  • Global Variome shared LOVD
  • LRG_483

Gene info

• Identity
  HGNC:8138
• Gene
  ONECUT1
• Long gene name
  one cut homeobox 1
• Synonyms gene
  • HNF6
  • HNF6A
• Synonyms gene name
  • one cut domain, family member 1
• Synonyms
  • HNF-6
• GenBank acession
  • U77975
• Locus
  15q21.3
• Discovery year
  2000-02-11
• Entrez gene record
  3175
• Pubmed identfication
  • 8887657
  • 8790352
• Classification
  • CUT class homeoboxes and pseudogenes
• VEGA ID
  OTTHUMG00000131899

Gene info

• Identity
  HGNC:35296
• Gene
  MIR1302-4
• Long gene name
  microRNA 1302-4
• Synonyms gene
  • MIRN1302-4
• Synonyms
  • hsa-mir-1302-4
• Locus
  2q33.3
• Discovery year
  2008-11-03
• Entrez gene record
  100302130
• RefSeq identity
  • NR_031633
• Classification
  • MicroRNA MIR1302 family

Gene info

• Identity
  HGNC:37522
• Gene
  PIRC18
• Long gene name
  piwi-interacting RNA cluster 18
• Locus
  4
• Discovery year
  2009-11-05
• Entrez gene record
  100313906
• Pubmed identfication
  • 17881367
• Classification
  • Piwi-interacting RNA clusters

Gene info

• Identity
  HGNC:37520
• Gene
  PIRC16
• Long gene name
  piwi-interacting RNA cluster 16
• Locus
  4
• Discovery year
  2009-11-05
• Entrez gene record
  100313849
• Pubmed identfication
  • 17881367
• Classification
  • Piwi-interacting RNA clusters

Gene info

• Identity
  HGNC:32992
• Gene
  SNORD114-4
• Long gene name
  small nucleolar RNA, C/D box 114-4
• Synonyms
  • 14q(II-4)
• Locus
  14q32.31
• Discovery year
  2006-09-26
• Entrez gene record
  767580
• Pubmed identfication
  • 12045206
• RefSeq identity
  • NR_003196.1
• Classification
  • Small nucleolar RNAs, C/D box

Gene info

• Identity
  HGNC:5809
• Gene
  IGKV2OR2-4
• Long gene name
  immunoglobulin kappa variable 2/OR2-4 (pseudogene)
• Synonyms gene name
  • immunoglobulin kappa variable 2/OR2-4
  • immunoglobulin kappa variable 2/OR2-4 pseudogene
• Synonyms
  • IGKV2/OR2-4
• GenBank acession
  • X51883
• Locus
  2q11.2
• Discovery year
  2000-04-18
• Entrez gene record
  28858
• Pubmed identfication
  • 2111145
• Classification
  • Immunoglobulin kappa (IGK) orphons

Gene info

• Identity
  HGNC:33687
• Gene
  MIR941-4
• Long gene name
  microRNA 941-4
• Synonyms gene
  • MIRN941-4
• Synonyms
  • hsa-mir-941-4
• Locus
  20q13.33
• Discovery year
  2007-10-24
• Entrez gene record
  100126330
• RefSeq identity
  • NR_040032
• Classification
  • MicroRNAs

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