HMBS Antibody

• Catalog number
  bs-9068R
• Price
  Please ask
• Size
  0.1ml

• Long name
  HMBS Primary Polyclonal Antibody
• Also known as
  HMBS PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  HMBS
• Specificity
  This is a highly specific antibody against HMBS.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human HMBS/PBGD
• Gene ID number
  3145
• Tested Applications
  WB, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  PBGD, also designated hydroxymethylbilane synthase, is a cytoplasmic enzyme found in the heme synthesis pathway. PBGD belongs to the HMBS (hydroxymethylbilane synthase) family. Deficiency of PBGD causes errors in pyrrole metabolism, which in turn leads to an inherited autosomal disorder called acute intermittent porphyria (AIP). AIP is characterized by acute attacks of neurological dysfunctions with hypertension, tachycardia, peripheral neurologic disturbances, abdominal pain and excessive amounts of aminolevulinic acid and porphobilinogen in the urine.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  HEM3_HUMAN; HMBS; Hydroxymethylbilane synthase; PBG D; PBG-D; PBGD; Porphobilinogen deaminase; Pre uroporphyrinogen synthase; Pre-uroporphyrinogen synthase; UPS; Uroporphyrinogen I synthase; Uroporphyrinogen I synthetase.
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  HMBS  
• Gene symbol
  HMBS
• Short name
  Anti-HMBS
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  HMBS Polyclonal Antibody
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:4982
• Gene
  HMBS
• Long gene name
  hydroxymethylbilane synthase
• Synonyms gene
  • PBGD
  • UPS
  • PORC
• Synonyms gene name
  • uroporphyrinogen I synthase
  • porphobilinogen deaminase
  • porphyria, acute; Chester type
• GenBank acession
  • X04808
• Locus
  11q23.3
• Discovery year
  1986-01-01
• Entrez gene record
  3145
• Pubmed identfication
  • 8432552
  • 17298217
• RefSeq identity
  • NM_000190
• VEGA ID
  OTTHUMG00000168295
• Locus Specific Databases
  • LRG_1076

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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