HLCL 61 hydrochloride

HLCL 61 hydrochloride is available 4 times from Biovision labs

B1209-25 | HLCL-61 hydrochloridesize: 25 mg | 711.42 USD

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B1209-5 | HLCL-61 hydrochloridesize: 5 mg | 311.61 USD

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B1209-25 | HLCL-61 hydrochloride for cell activationsize: 25 mg | 640.87 USD

  • Catalog number
    B1209-25
  • Supplier
  • Price
    640.87 USD
  • Size
    25 mg
  • Additional description
    For cells, cell lines and tissues in culture till half confluency.
  • Gene target
  • Short name
    HLCL-61 hydrochloride for activation
  • Technique
    activation
  • Alternative name
    HLCL-61 hydrochloride to measure cellular activation
  • Tissue
    cell
1. Gene info
Additional information
Product images

B1209-5 | HLCL-61 hydrochloride for cell activationsize: 5 mg | 205.78 USD

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  • Description
    HLCL-61 is a potent and selective PRMT5 (potent arginine methyltransferase 5) inhibitor. It shows no inhibitory activity against the type I (PRMT1 and PRMT4) and type II (PRMT7) PRMT family members.  In vitro data shows HLCL-61 effectively inhibits symmetric arginine demethylation of histones H3 and H4 in AML samples. HLCL-61 treatment of cells showed decrease in cell vitality and effective in apoptosis promotion in MV-11 and THP-1 cells after 48 hours.
  • Peptide sequence
    N/A
  • CAS number
    586395-74-6 (free base). 
  • Molecular weight
    380.92
  • Category
    Biochemicals
  • Other name
    1-(9-ethyl-9H-carbazol-3-yl)-N-(2-methoxybenzyl)methanamine hydrochloride
  • Molecular formula
    C₂₃H₂₅ClN₂O 
  • Physical appearance
    Crystalline Solid
  • Supplied with
    N/A
  • Is this a salt?
    Yes
  • Is it cell-permeable?
    Yes
  • Purification
    ≥98% by HPLC
  • Reconstitute instructions
    DMSO(>20 mg/ml)
  • Storage condition
    -20°C
  • Shipping condition
    gel pack
  • Maximum time for storage
    36 months
  • Storage instructions
    Protect from air and light
  • Alternate Name/Synonyms
    1-(9-ethyl-9H-carbazol-3-yl)-N-(2-methoxybenzyl)methanamine hydrochloride
  • Appearance
    Crystalline Solid
  • Formulation
    N/A
  • CAS Number
    586395-74-6 (free base).
  • Molecular Formula
    C₂₃H₂₅ClN₂O
  • Molecular Weight
    380.92
  • Purity
    ≥98% by HPLC
  • Solubility/Reconstitution Instructions
    DMSO(>20 mg/ml)
  • Handling
    Protect from air and light
  • Tagline
    A selective PRMT5(potent arginine methyltransferase 5) inhibitor
  • Storage Temp.
    -20°C
  • Shipping Conditions
    gel pack
  • Shelf Life
    36 months
  • MDL Number
    N/A
  • PubChem CID
    17208222
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