Histone H4 Peptide, tetra-acetylated, biotin conjugate

  • Catalog number
    7144-01
  • Price
    Please ask
  • Size
    100 µg
  • Description
    Tetra-acetylated Biotin conjugated H4 peptide for multiple applications. Histone H4 is one of the core components of the nucleosome. Lysine N-acetylation is a dynamic, reversible and tightly regulated histone modification that plays a major role in chromatin remodeling and in the regulation of gene expression in various cellular functions. Acetylation of histone H4 can occur at several different lysine positions in the histone tail, and is performed by Histone Acetyltransferases (HATs). Acetylation of histones is often associated with transcriptional activation. This synthetic peptide is tetra-acetylated and has a biotinylated lysine at the C-terminus.
  • Product Highlights
    SOURCE: Synthetic PURITY: ≥ 95% by HPLC MOLECULAR WEIGHT: ~ 2.73 kDa FORM: Lyophilized powder FORMULATION: Peptide was dissolved in distilled water at 1 mg/ml and re-lyophilized to powder form RECONSTITUTION: Centrifuge the vial prior to opening. Reconstitute in 1 ml/mg dH2O. Avoid freezing and thawing cycles. Store at -20°C for 6 months. KEY APPLICATIONS: The suggested applications include Immunoprecipitation, affinity precipitation, and as substrate for histone modified enzymes, etc. AMINO ACID SEQUENCE: One letter code: ARTKQTARKSTGGKAPR-K(Ac)-QLA-GGK(Biotin)-NH2 Three letter code: H - Ala - Arg - Thr - Lys - Gln - Thr - Ala - Arg - Lys - Ser - Thr - Gly - Gly - Lys - Ala - Pro - Arg - Lys(Ac) - Gln - Leu - Ala - Gly - Gly - Lys(Biotin) - NH2
  • Storage Temp
    -20°C
  • Shipping
    gel pack
  • Shelf Life
    6 months
  • Notes
    For research use only. Not to be used for human or animal treatment or consumption.
  • Properties
    Biotin conjugates can be detected by horseradish peroxidase, alkaline phosphatase substrates or anti biotin conjugated antibodies. Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA. To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1.6.
  • Conjugation
    Biotinylated
  • Additional description
    Peptides short amino acid chains or epitopes or blocking antagonists. The shortest peptides are dipeptides, consisting of 2 amino acids joined by a single peptide bond, followed by tripeptides, tetra peptides, ... till polypeptides that are long, continuous, and unbranched synthetic peptide chains. These biological oligomers and polymers can be Solid-phase peptide synthesis (SPPS), or in continue produced for custom peptide synthesis projects. The High-efficiency solid phase peptide synthesis (HE-SPPS) is give very low production costs.
  • Gene target
  • Short name
    Histone H4 Peptide, tetra-acetylated, conjugate
  • Technique
    peptide, peptides
  • Label
    Biotin
  • Alternative name
    Histone H4 short protein sequence, tetra-acetylated, biotinilated conjugate
  • Alternative technique
    peptides
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