HHATL/GUP1 Antibody, FITC Conjugated

  • Catalog number
    bs-12315R-FITC
  • Price
    Please ask
  • Size
    0.1ml
  • Long name
    HHATL/GUP1 Polyclonal Antibody, FITC Conjugated
  • Category
    Conjugated Primary Antibodies
  • Conjugation
    FITC
  • Host Organism
    Rabbit (Oryctolagus cuniculus)
  • Target Antigen
    HHATL/GUP1
  • Specificity
    This is a highly specific antibody against HHATL/GUP1.
  • Modification
    Unmodified
  • Modification site
    None
  • Clonality
    Polyclonal
  • Clone
    Polyclonal antibody
  • Concentration
    1ug per 1ul
  • Source
    KLH conjugated synthetic peptide derived from human HHATL/GUP1
  • Gene ID number
    57467
  • Tested applications
    IF(IHC-P)
  • Recommended dilutions
    IF(IHC-P)(1:50-200)
  • Crossreactivity
    Human, Mouse, Rat
  • Crossreactive species details
    Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
  • Antigen background
    GUP1 is a 504 amino acid multipass membrane protein of the endoplasmic reticulum that functions as a membrane bound O-acyltransferase. With specific expression in heart, GUP1 negatively regulates amino-terminal palmitoylation of Shh by HHAT, a protein that is required for Shh signaling. Deletion of the gene encoding GUP1 results in higher sensibility to specific sphinogolipid biosynthesis inhibitors and resistance to ergosterol biosynthesis inhibitors, indicating that GUP1 is an essential component in lipid metabolism. Also, GUP1 also seems to be important for cell wall assembly and stability due to evidence in Saccharomyces cerevisiae GUP1 mutants, which exhibit altered plasma membrane lipid composition and membrane potential.
  • Purification method
    This antibody was purified via Protein A.
  • Storage conditions
    Keep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
  • Excitation Emission
    494nm/518nm
  • Synonyms
    C3orf3; Glycerol uptake/transporter homolog; GUP1; GUP1 glycerol uptake/transporter homolog; Hedgehog acyltransferase like; Hedgehog acyltransferase-like protein; Hhatl; HHATL_HUMAN; KIAA1173; MBOAT3; Membrane bound O acyltransferase domain containing 3; MSTP002; OACT3; Protein-cysteine N-palmitoyltransferase HHAT-like protein.
  • Properties
    If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS. When excited at 488 nanometers, FITC has a green emission that's usually collected at 530 nanometers, the FL1 detector of a FACSCalibur or FACScan. FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light. For fluorescent microscopy applications, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept. Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes.
  • Additional conjugation
    Anti-FITC Antibody
  • French translation
    anticorps
  • Gene target
  • Gene symbol
    HHATL, HHATL-AS1, MYZAP
  • Short name
    Anti-HHATL/GUP1
  • Technique
    Antibody, FITC, antibodies against human proteins, antibodies for, antibody Conjugates, Fluorescein
  • Isotype
    Immunoglobulin G (IgG)
  • Label
    FITC
  • Alternative name
    Anti-HHATL/GUP1 PAb FITC
  • Alternative technique
    antibodies, fluorescine
Gene info
Gene info
  • Identity
  • Gene
  • Long gene name
    HHATL antisense RNA 1
  • Synonyms gene name
    • HHATL antisense RNA 1 (non-protein coding)
  • Locus
  • Discovery year
    2011-07-27
  • Classification
    • Antisense RNAs
  • VEGA ID
Gene info
MeSH Data
  • Name
  • Concept
    Scope note: Test for tissue antigen using either a direct method, by conjugation of antibody with fluorescent dye (FLUORESCENT ANTIBODY TECHNIQUE, DIRECT) or an indirect method, by formation of antigen-antibody complex which is then labeled with fluorescein-conjugated anti-immunoglobulin antibody (FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT). The tissue is then examined by fluorescence microscopy.
  • Tree numbers
    • E01.370.225.500.607.512.240
    • E01.370.225.750.551.512.240
    • E05.200.500.607.512.240
    • E05.200.750.551.512.240
    • E05.478.583.375
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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