HER4 (Tyr1284) Antibody

• Catalog number
  bs-3220R
• Price
  Please ask
• Size
  0.1ml

• Long name
  HER4 (Tyr1284) Primary Polyclonal Antibody
• Also known as
  HER4 (Tyr1284) PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  HER4 Tyr1284
• Specificity
  This is a highly specific antibody against HER4 Tyr1284.
• Modification s
  Phosphorylation
• Modification site s
  Tyr1284
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  KLH conjugated synthetic phosphopeptide derived from human HER4 around the phosphorylation site of Tyr1284
• Gene ID number
  2066
• Tested Applications
  WB, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  This gene is a member of the Tyr protein kinase family and the epidermal growth factor receptor subfamily. It encodes a single-pass type I membrane protein with multiple cysteine rich domains, a transmembrane domain, a tyrosine kinase domain, a phosphotidylinositol-3 kinase binding site and a PDZ domain binding motif. The protein binds to and is activated by neuregulins and other factors and induces a variety of cellular responses including mitogenesis and differentiation. Multiple proteolytic events allow for the release of a cytoplasmic fragment and an extracellular fragment. Mutations in this gene have been associated with cancer. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. [provided by RefSeq, Jul 2008].
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  ErbB 4 phospho Y1284; p-ErbB 4 phospho Y1284; ErbB4; HER 4; HER4; Avian erythroblastic leukemia viral oncogene homolog 4; Avian erythroblastic leukemia viral v erb b2 oncogene homolog 4; MGC138404; P180erbB4; Receptor protein tyrosine kinase erbB 4 precursor; Receptor tyrosine protein kinase erbB 4;Tyrosine kinase type cell surface receptor HER4; v erb a avian erythroblastic leukemia viral oncogene homolog like 4; v erb a erythroblastic leukemia viral oncogene homolog 4; Verba avian erythroblastic leukemia viral oncogene homolog like 4; Verba erythroblastic leukemia viral oncogene homolog 4; VERBB2.
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  HER4   Tyr1284  
• Gene symbol
  ERBB4
• Short name
  Anti-HER4 Tyr1284
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  HER4 (Tyr1284) Polyclonal Antibody
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:3432
• Gene
  ERBB4
• Long gene name
  erb-b2 receptor tyrosine kinase 4
• Synonyms gene name
  • v-erb-a avian erythroblastic leukemia viral oncogene homolog-like 4
  • v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 4
• Synonyms
  • ALS19
  • HER4
• Synonyms name
  • human epidermal growth factor receptor 4
• GenBank acession
  • L07868
• Locus
  2q34
• Discovery year
  1995-09-07
• Entrez gene record
  2066
• Pubmed identfication
  • 7700649
  • 17018285
• RefSeq identity
  • NM_001042599
• Classification
  • Erb-b2 receptor tyrosine kinases
  • MicroRNA protein coding host genes
• VEGA ID
  OTTHUMG00000133012

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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