HDAC7 (Ser358) Antibody, ALEXA FLUOR 350

  • Catalog number
    bs-3216R-A350
  • Price
    Please ask
  • Size
    100ul
  • Long name
    HDAC7 (Ser358) Polyclonal Antibody, ALEXA FLUOR 350 Conjugated
  • Also known as
    Anti-HDAC7 Ser358 PAb ALEXA FLUOR 350
  • Category
    Conjugated Primary Antibodies
  • Conjugated with
    ALEXA FLUOR® 350
  • Host Organism
    Rabbit (Oryctolagus cuniculus)
  • Target Antigen
    HDAC7 Ser358
  • Specificity
    This is a highly specific antibody against HDAC7 Ser358.
  • Modification
    Phosphorylation
  • Modification Site
    Ser358
  • Clonality
    Polyclonal
  • Clone
    Polyclonal antibody
  • Concentration
    1ug per 1ul
  • Source
    KLH conjugated synthetic phosphopeptide derived from human HDAC7 around the phosphorylation site of Ser358
  • Tested applications
    IF(IHC-P)
  • Recommended dilutions
    IF(IHC-P)(1:50-200)
  • Crossreactivity
    Human, Mouse, Rat
  • Cross reactive species details
    Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
  • Background of the antigen
    HDAC7 is a member of the class II mammalian histone deacetylases, which plays an important role in modulating the eukaryotic chromatin structure. Human HDAC7 is composed of 912 amino acid residues. Although HDAC7 is localized mostly to the cell nucleus, it is also found in the cytoplasm, suggesting nucleo-cytoplasmic shuttling. The histone deacetylase activity of HDAC7 maps to a carboxy-terminal domain and is dependent on interaction with class I HDACs in the nucleus. It is an active component of different transcriptional corepressor complexes that can be recruited to specific promoter regions via interactions with a growing number of sequence specific transcriptional factors. HDAC7 catalyzes removal of acetyl-groups from acetyl-lysines of histones and promotes compaction of chromatin in these regions, leading to the inhibition of gene transcription.
  • Purification
    Purified by Protein A.
  • Storage conditions
    Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
  • Excitation emission
    343nm/442nm
  • Synonyms
    HDAC7 phospho S358; HDAC7 phospho Ser358; p-HDAC7 Ser358; HD 7a; HD7a; HDAC 7; HDAC 7A; HDAC7; HDAC7A; Histone deacetylase 7; Histone deacetylase 7A; DKFZP586J0917; OTTHUMP00000202813; OTTHUMP00000202814; FLJ99588; HDAC7_HUMAN.
  • Properties
    For facs or microscopy Alexa 1 conjugate. Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
  • Conjugation
    Alexa Fluor, ALEXA FLUOR 350
  • French translation
    anticorps
  • Gene target
    HDAC7   Ser358  
  • Gene symbol
    HDAC7
  • Short name
    Anti-HDAC7 Ser358
  • Technique
    Antibody, antibodies against human proteins, antibodies for
  • Isotype
    Immunoglobulin G (IgG)
  • Label
    ALEXA FLUOR 350
  • Alternative name
    HDAC7 (Ser358) Polyclonal Antibody, ALEXA FLUOR 350
  • Alternative technique
    antibodies
  • Alternative to gene target
    histone deacetylase 7, HDAC7 and IDBG-29060 and ENSG00000061273 and 51564, NAD-dependent histone deacetylase activity (H3-K18 specific), nuclei, Hdac7 and IDBG-179042 and ENSMUSG00000022475 and 56233, HDAC7 and IDBG-633011 and ENSBTAG00000026819 and 509843
Gene info
MeSH Data
  • Name
  • Concept
    Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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