HDAC6 (Ser22) Antibody, ALEXA FLUOR 647
-
Catalog number
bs-3215R-A647
-
Price
Please ask
-
Size
100ul
-
-
Long name
HDAC6 (Ser22) Polyclonal Antibody, ALEXA FLUOR 647 Conjugated
-
Also known as
Anti-HDAC6 Ser22 PAb ALEXA FLUOR 647
-
Category
Conjugated Primary Antibodies
-
Conjugated with
ALEXA FLUOR® 647
-
Host Organism
Rabbit (Oryctolagus cuniculus)
-
Target Antigen
HDAC6 Ser22
-
Specificity
This is a highly specific antibody against HDAC6 Ser22.
-
Modification
Phosphorylation
-
Modification Site
Ser22
-
Clonality
Polyclonal
-
Clone
Polyclonal antibody
-
Concentration
1ug per 1ul
-
Source
KLH conjugated synthetic phosphopeptide derived from human HDAC6 around the phosphorylation site of Ser22
-
Gene ID Number
10013
-
Tested applications
IF(IHC-P)
-
Recommended dilutions
IF(IHC-P)(1:50-200)
-
Crossreactivity
Human
-
Cross reactive species details
Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
-
Background of the antigen
HDAC6 is a member of the class II mammalian histone deacetylases. Human HDAC6 is composed of 1215 amino acid residues. It possesses two separate putative catalytic domains. Both catalytic domains are fully functional HDACs and contribute independently to the overall activity of HDAC6 protein. A very potent NES is present at the amino-terminus of HDAC6, which was found to play an important role in regulating the shuttling of HDAC6 protein between cytoplasm and nucleus. The shuttling process may be a critical regulatory mechanism of HDAC6 function. The expression of HDAC6 is tightly linked to the state of cell differentiation. HDAC6 may participate in coordinating expression of a group of genes involved in the remodelling of chromatin during cell differentiation.
-
Purification
Purified by Protein A.
-
Storage conditions
Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
-
Excitation emission
650nm/665nm
-
Synonyms
HDAC6 phospho S22; HDAC6 phospho Ser22; p-HDAC6 Ser22; HD 6; HD6; HDAC 6; Histone deacetylase 6; HD6; Histone deacetylase 6; JM 21; JM21; KIAA0901; FLJ16239; HDAC6_HUMAN.
-
Properties
For facs or microscopy Alexa 1 conjugate. Alexa Fluor 633 is a practical alternative to APC as well as Cy5. Bioss Primary Conjugated Antibodies. ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode. It is detected in the FL4 detector of the core's upgraded 2-laser FACScans. Like other Alexa Fluor dyes, the Anti-HDAC6 Ser22 exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
-
Conjugation
Alexa Fluor, ALEXA FLUOR 647
-
French translation
anticorps
-
Gene target
-
Gene symbol
HDAC6
-
Short name
Anti-HDAC6 Ser22
-
Technique
Antibody, antibodies against human proteins, antibodies for
-
Isotype
Immunoglobulin G (IgG)
-
Label
ALEXA FLUOR 647
-
Alternative name
HDAC6 (Ser22) Polyclonal Antibody, ALEXA FLUOR 647
-
Alternative technique
antibodies
-
Alternative to gene target
histone deacetylase 6, CPBHM and HD6 and PPP1R90, HDAC6 and IDBG-63929 and ENSG00000094631 and 10013, NAD-dependent histone deacetylase activity (H3-K18 specific), nuclei, Hdac6 and IDBG-129835 and ENSMUSG00000031161 and 15185, BT.76413 and IDBG-636881 and ENSBTAG00000013244 and 513602
-
Gene info
-
Identity
-
Gene
-
Long gene name
histone deacetylase 6
-
Synonyms
-
Synonyms name
-
GenBank acession
-
Locus
-
Discovery year
2000-11-28
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- Histone deacetylases, class IIB
- Protein phosphatase 1 regulatory subunits
-
VEGA ID
-
Locus Specific Databases
MeSH Data
-
Name
-
Concept
Scope note:
Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
-
Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
-
Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
Product images
Similar products