APE (APEX, APEX1, APEX nuclease multifunctional DNA repair enzyme, APX, APE1, APEN, HAP1, REF1, REF-1, AP lyase, AP endonuclease class I, DNA apurinic/apyrimidinic exonuclease/ lyase) (Control Peptide)

• Catalog number
  MBS653972
• Price
  Please ask
• Size
  0,1 mg

• Other size
  please contact us to order other different size
• Description
  Isotype or positive controls by peptides, antibodies and deactivated samples. Enzymes are cleaving the substrate. If the substrate is DNA they are called restriction enzymes. Activating enzymes will cut off the domain that is biological active to become functional. Peptides short amino acid chains or epitopes or blocking antagonists. The shortest peptides are dipeptides, consisting of 2 amino acids joined by a single peptide bond, followed by tripeptides, tetra peptides, ... till polypeptides that are long, continuous, and unbranched synthetic peptide chains. These biological oligomers and polymers can be Solid-phase peptide synthesis (SPPS), or in continue produced for custom peptide synthesis projects. The High-efficiency solid phase peptide synthesis (HE-SPPS) is give very low production costs.

• Gene target
  APE   APEX   APEX1   APEX   nuclease   multifunctional   DNA   repair   APX   APE1   APEN   HAP1   REF1   REF-1   lyase   endonuclease   class   DNA   apurinic/apyrimidinic   exonuclease   lyase   Peptide  
• Gene symbol
  APEX1, TFPI2, PRKDC, HLA-DOA, ALYREF, HAP1, CCDC88A, IGHVII-1-1, MIR1-1
• Short name
  APE (APEX, APEX1, APEX nuclease multifunctional DNA repair enzyme, APX, APE1, APEN, HAP1, REF1, REF-1, AP lyase, AP endonuclease class I, DNA apurinic/apyrimidinic exonuclease/ lyase) (Control Peptide)
• Technique
  Control, peptide, Enzyme, dna, controls, enzymes, peptides
• Label
  AP
• Alternative name
  APE (APEX, APEX1, APEX nuclease multifunctional Desoxyribonucleic acid repair enzyme, APX, APE1, APEN, HAP1, REF1, REF-1, AP lyase, AP endonuclease class I, Desoxyribonucleic acid apurinic/apyrimidinic exonuclease/ lyase) (reference short protein sequence)
• Alternative technique
  peptides, controls, enzymes
• Tissue
  control

Gene info

• Identity
  HGNC:587
• Gene
  APEX1
• Long gene name
  apurinic/apyrimidinic endodeoxyribonuclease 1
• Synonyms gene
  • APEX
• Synonyms gene name
  • APEX nuclease (multifunctional DNA repair enzyme)
  • APEX nuclease (multifunctional DNA repair enzyme) 1
• Synonyms
  • APE
  • REF1
  • HAP1
  • APX
  • APEN
  • REF-1
  • APE-1
• GenBank acession
  • X59764
• Locus
  14q11.2
• Discovery year
  1997-05-22
• Entrez gene record
  328
• RefSeq identity
  • NM_001641
• Classification
  • SET complex
  • Endoribonucleases
• VEGA ID
  OTTHUMG00000029544
• Locus Specific Databases
  • ALSOD, the Amyotrophic Lateral Sclerosis Online Genetic Database

Gene info

• Identity
  HGNC:11761
• Gene
  TFPI2
• Long gene name
  tissue factor pathway inhibitor 2
• Synonyms
  • PP5
  • TFPI-2
  • REF1
• GenBank acession
  • L27624
• Locus
  7q21.3
• Discovery year
  1999-07-14
• Entrez gene record
  7980
• Pubmed identfication
  • 7896752
  • 8945635
• RefSeq identity
  • NM_006528
• VEGA ID
  OTTHUMG00000022963
• Locus Specific Databases
  • LRG_647

Gene info

• Identity
  HGNC:9413
• Gene
  PRKDC
• Long gene name
  protein kinase, DNA-activated, catalytic subunit
• Synonyms gene
  • HYRC
  • HYRC1
• Synonyms gene name
  • protein kinase, DNA-activated, catalytic polypeptide
• Synonyms
  • DNPK1
  • p350
  • DNAPK
  • XRCC7
  • DNA-PKcs
  • DNAPKc
  • DNA-PKC
  • p460
• Synonyms name
  • DNA-dependent protein kinase catalytic subunit
• Locus
  8q11.21
• Discovery year
  1993-11-09
• Entrez gene record
  5591
• Pubmed identfication
  • 7638222
• RefSeq identity
  • NM_001081640
• Classification
  • Armadillo like helical domain containing
• VEGA ID
  OTTHUMG00000164239
• Locus Specific Databases
  • LRG_162

Gene info

• Identity
  HGNC:4936
• Gene
  HLA-DOA
• Long gene name
  major histocompatibility complex, class II, DO alpha
• Synonyms gene
  • HLA-DZA
  • HLA-DNA
• Synonyms
  • HLA-D0-alpha
• GenBank acession
  • M31525
• Locus
  6p21.32
• Discovery year
  2001-06-22
• Entrez gene record
  3111
• Pubmed identfication
  • 2370084
• RefSeq identity
  • NM_002119
• Classification
  • C1-set domain containing
  • Histocompatibility complex
• VEGA ID
  OTTHUMG00000031211
• Locus Specific Databases
  • IMGT/HLA Database

Gene info

• Identity
  HGNC:19071
• Gene
  ALYREF
• Long gene name
  Aly/REF export factor
• Synonyms gene
  • THOC4
• Synonyms gene name
  • THO complex 4
• Synonyms
  • ALY
  • BEF
  • ALY/REF
  • REF
• GenBank acession
  • AF047002
• Locus
  17q25.3
• Discovery year
  2002-12-09
• Entrez gene record
  10189
• Pubmed identfication
  • 11032328
  • 15998806
• RefSeq identity
  • NM_005782
• Classification
  • THO complex
  • RNA binding motif containing
• VEGA ID
  OTTHUMG00000160470

Gene info

• Identity
  HGNC:4812
• Gene
  HAP1
• Long gene name
  huntingtin associated protein 1
• Synonyms gene
  • HAP2
• Synonyms gene name
  • huntingtin-associated protein 1
• Synonyms
  • HLP
  • hHLP1
  • HIP5
• Synonyms name
  • neuroan 1
• GenBank acession
  • AF040723
• Locus
  17q21.2
• Discovery year
  1999-04-28
• Entrez gene record
  9001
• Pubmed identfication
  • 7477378
  • 9668110
• RefSeq identity
  • NM_003949
• VEGA ID
  OTTHUMG00000133498

Gene info

• Identity
  HGNC:25523
• Gene
  CCDC88A
• Long gene name
  coiled-coil domain containing 88A
• Synonyms gene
  • KIAA1212
• Synonyms gene name
  • KIAA1212
• Synonyms
  • FLJ10392
  • APE
  • GIV
  • HkRP1
  • GRDN
• Synonyms name
  • Galpha-interacting vesicle-associated protein
  • Akt-phosphorylation enhancer
  • girdin
  • girders of actin filaments
• GenBank acession
  • AB033038
  • AF112218
• Locus
  2p16.1
• Discovery year
  2004-01-13
• Entrez gene record
  55704
• Pubmed identfication
  • 15749703
  • 15753085
• RefSeq identity
  • NM_017571
• VEGA ID
  OTTHUMG00000151915

Gene info

• Identity
  HGNC:5670
• Gene
  IGHVII-1-1
• Long gene name
  immunoglobulin heavy variable (II)-1-1 (pseudogene)
• Synonyms gene name
  • immunoglobulin heavy variable (II)-1-1
  • immunoglobulin heavy variable (II)-1-1 pseudogene
• Synonyms
  • IGHV(II)-1-1
• GenBank acession
  • AB019441
• Locus
  14q32.33
• Discovery year
  2000-04-17
• Entrez gene record
  28377
• RefSeq identity
  • NG_001019
• Classification
  • Immunoglobulin heavy locus at 14q32.33
• VEGA ID
  OTTHUMG00000152325

Gene info

• Identity
  HGNC:31499
• Gene
  MIR1-1
• Long gene name
  microRNA 1-1
• Synonyms gene
  • MIRN1-1
• Synonyms
  • hsa-mir-1-1
• Locus
  20q13.33
• Discovery year
  2004-04-23
• Entrez gene record
  406904
• RefSeq identity
  • NR_029780
• Classification
  • MicroRNA MIR1/206 family

MeSH Data

• Name
  Targeted Gene Repair
• Concept
  Scope note: A technique which uses synthetic oligonucleotides to direct the cell's inherent DNA repair system to correct a mutation at a specific site in an episome or chromosome.
• Tree numbers
  • E02.095.301.500
  • E05.393.420.301.500
  • E05.393.420.601.575.500
• Qualifiers
  legislation & jurisprudence, ethics, mortality, psychology, trends, veterinary, history, classification, economics, instrumentation, methods, nursing, standards, adverse effects, statistics & numerical data

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