Hamster Anti-Mouse CD28-UNLB

• Catalog number
  MBS673305
• Price
  Please ask
• Size
  0.5 mg

• Products_type
  Antibody
• Products_short_name
  [CD28]
• Products_name_syn
  [Hamster Anti-Mouse CD28 - Purified, Unlabeled Antibody; Hamster Anti-Mouse CD28]
• Other_names
  [CD28; T-cell-specific surface glycoprotein CD28; T-cell-specific surface glycoprotein CD28; OTTMUSP00000002157; CD28 antigen]
• Other_gene_names
  [Cd28; Cd28]
• Clonality
  Monoclonal
• Clone
  [PV-1]
• Reactivity
  Mouse
• Specificity
  Murine CD28 CD28 is a type I disulfide-linked homodimer that is constitutively expressed on most thymocytes, at low density on nearly all CD4^+ and CD8^+ peripheral T lymphocytes, and at very low levels on NK cells. Its expression is upregulated upon T-cell activation.1-4 CD28 is a ligand for CD80/B7-1 and CD86/B7-2 on B cells and other antigen presenting cells, and plays an important role in the interaction between T cells and B cells.^5 CD28 is a co-stimulatory receptor involved in many, but not all, T-cell independent immune responses.^6-9
• Form
  Purified (UNLB) Antibody
• Storage_stability
  The purified (UNLB) antibody is supplied as 0.5 mg of purified immunoglobulin in 1.0 mL of 100 mM borate buffered saline, pH 8.2. No preservatives or amine-containing buffer salts added. Store at 2-8 degree C. The fluorescein (FITC) conjugate is supplied as 0.5 mg in 1.0 mL of PBS/NaN3. Store at 2-8 degree C. The biotin (BIOT) conjugate is supplied as 0.5 mg in 1.0 mL of PBS/NaN3. Store at 2-8 degree C. The R-phycoerythrin (R-PE) conjugate is supplied as 0.1 mg in 1.0 mL or 0.2 mg in 2.0 mL of PBS/NaN3 and a stabilizing agent. Store at 2-8 degree C. Do not freeze! The allophycocyanin (APC) conjugate is supplied as 0.1 mg in 1.0 mL of PBS/NaN3 and a stabilizing agent. Store at 2-8 degree C. Do not freeze! The Spectral Red (SPRD) conjugate is supplied as 0.1 mg in 1.0 mL of PBS/NaN3 and a stabilizing agent. Store at 2-8 degree C. Do not freeze! The low endotoxin, azide-free (LE/AF) antibody is supplied as 0.5 mg purified immunoglobulin in 1.0 mL of PBS. Aliquot and store at or below -20 degree C. Protect conjugated forms from light. Aliquot and freeze the low endotoxin, azide-free product at -20 degree C immediately upon receipt. Each reagent is stable for the period shown on the bottle label if stored as directed.
• Tested_application
  Flow Cytometry; Immunoprecipitation
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  Armenian of Syrian hamster monoclonal IgGs are useful antibodies for double staining your IHC samples. Using mabs or monoclonal antibodies has a lot of advantages for Flow cytometry.
• Test
  Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
• Latin name
  Mus musculus

• Gene target
  CD28-UNLB  
• Gene symbol
  CD28
• Short name
  Anti-Mouse CD28-UNLB
• Technique
  anti-, Mouse, anti, antibody to, antibodies, mouses
• Host
  Armenian Hamster
• Isotype
  Armenian Hamster IgG
• Species
  Mouse, Hamsters, Mouses
• Alternative name
  Hamster Antibody toMouse CD28 molecule-UNLB
• Alternative technique
  murine, antibodies
• Alternative to gene target
  CD28 molecule, Tp44, CD28 and IDBG-79183 and ENSG00000178562 and 940, identical protein binding, Cell surfaces, Cd28 and IDBG-159608 and ENSMUSG00000026012 and 12487, CD28 and IDBG-643371 and ENSBTAG00000007445 and 281050

Gene info

• Identity
  HGNC:1653
• Gene
  CD28
• Long gene name
  CD28 molecule
• Synonyms gene name
  • CD28 antigen (Tp44)
• Synonyms name
  • T-cell-specific surface glycoprotein
• GenBank acession
  • J02988
• Locus
  2q33.2
• Discovery year
  1988-05-11
• Entrez gene record
  940
• Pubmed identfication
  • 1355979
• RefSeq identity
  • NM_006139
• Classification
  • CD molecules
  • Ig-like cell adhesion molecule family
  • V-set domain containing
• VEGA ID
  OTTHUMG00000132878

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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