HAAO Antibody

• Catalog number
  bs-11695R
• Price
  Please ask
• Size
  0.1ml

• Long name
  HAAO Primary Polyclonal Antibody
• Also known as
  HAAO PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  HAAO
• Specificity
  This is a highly specific antibody against HAAO.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human HAAO
• Tested Applications
  WB, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  The 3-HAO family of proteins consists of intramolecular dioxygenases that contain non-heme ferrous iron. HAAO (3-hydroxyanthranilate 3,4-dioxygenase), also known as HAO or 3-HAO, is a 286 amino acid monomeric cytoplasmic protein that belongs to the 3-HAO family. Utilizing Fe2+ ions as a cofactor, HAAO participates in the formation of quinolinic acid (QUIN), and excitotoxin, by catalyzing the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde. HAAO may play a role in disorders that are associated with varying levels of QUIN expression, and is widely expressed in peripheral organs, including kidney and liver. Existing as two alternatively spliced isoforms, the gene encoding HAAO maps to human chromosome 2p21 and mouse chromosome 17 E4.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  3 HAO;3 hydroxyanthranilate 3 4 dioxygenase;3 hydroxyanthranilate dioxygenase;3 hydroxyanthranilate oxygenase;3 hydroxyanthranilic acid dioxygenase;3-HAO;3-hydroxyanthranilate 3;3-hydroxyanthranilate 3,4-dioxygenase;3-hydroxyanthranilate oxygenase;3-hydroxyanthranilic acid dioxygenase;3HAO_HUMAN;4-dioxygenase;haao;HAD;HAO.
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  HAAO  
• Gene symbol
  HAAO
• Short name
  Anti-HAAO
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  HAAO Polyclonal Antibody
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:4796
• Gene
  HAAO
• Long gene name
  3-hydroxyanthranilate 3,4-dioxygenase
• GenBank acession
  • Z29481
• Locus
  2p21
• Discovery year
  1999-12-14
• Entrez gene record
  23498
• Pubmed identfication
  • 7514594
  • 28792876
• VEGA ID
  OTTHUMG00000152348

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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