GW 6471 for cell activation

GW 6471 for cell activation is available 2 times from Biovision labs

9453-1 | GW-6471 for cell activationsize: 1 mg | 155.22 USD

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9453-5 | GW-6471 for cell activationsize: 5 mg | 436.26 USD

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  • Description
    GW-6471 is a potent PPARα antagonist (IC₅₀ = 240 nM). It drives the displacement of coactivators from PPARα and promotes the recruitment of co-repressor proteins like nuclear co-repressor. GW-6471 significantly prevents cardiomyocyte differentiation and results in the reduced expression of cardiac sarcomeric proteins and specific genes in a time-dependent manner.
  • Peptide sequence
    N/A
  • CAS number
    880635-03-0
  • Molecular weight
    619.67
  • Category
    Biochemicals
  • Other name
     N-((2S)-2-(((1Z)-1-Methyl-3-oxo-3-(4-(trifluoromethyl)phenyl)prop-1-enyl)amino)-3-(4-(2-(5-methyl-2-phenyl-1,3-oxazol-4-yl)ethoxy)phenyl)propyl)propanamide
  • Molecular formula
    C₃₅H₃₆F₃N₃O₄
  • Physical appearance
    Cream-colored solid
  • Supplied with
    N/A
  • Is this a salt?
    N/A
  • Is it cell-permeable?
    Yes
  • Purification
    ≥98%
  • Reconstitute instructions
    DMSO (~40 mg/ml) or EtOH (~10 mg/ml)
  • Storage condition
    -20°C
  • Shipping condition
    Gel pack
  • Maximum time for storage
    36 months
  • Storage instructions
    Protect from air and light
  • Additional description
    For cells, cell lines and tissues in culture till half confluency.
  • Gene target
  • Short name
    GW-6471 for activation
  • Technique
    activation
  • Alternative name
    GW-6471 to measure cellular activation
  • Tissue
    cell
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