GSK 2606414 for cell activation

GSK 2606414 for cell activation is available 2 times from Biovision labs

9467-25 | GSK-2606414 for cell activationsize: 25 mg | 737.61 USD

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9467-5 | GSK-2606414 for cell activationsize: 5 mg | 229.92 USD

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  • Description
    GSK-2606414 is a potent and selective inhibitor of protein kinase R-like ER kinase (PERK) with IC₅₀ value of 0.4 nM. Displays >1000-fold selectivity for PERK over HR1 and PKR. GSK-2606414 inhibits PERK activation in cells and inhibits the growth of a human tumor xenograft in mice.
  • Peptide sequence
    N/A
  • CAS number
    1337531-36-8
  • Molecular weight
    451.44
  • Category
    Biochemicals
  • Other name
    1-(5-(4-amino-7-methyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)indolin-1-yl)-2-(3-(trifluoromethyl)phenyl)ethanone
  • Molecular formula
    C₂₄H₂₀F₃N₅O
  • Physical appearance
    White solid
  • Supplied with
    N/A
  • Is this a salt?
    N/A
  • Is it cell-permeable?
    Yes
  • Purification
    ≥98% by HPLC
  • Reconstitute instructions
    DMSO (>30 mg/ml)
  • Storage condition
    -20°C
  • Shipping condition
    Gel pack
  • Maximum time for storage
    36 months
  • Storage instructions
    Protect from air and light
  • Additional description
    For cells, cell lines and tissues in culture till half confluency.
  • Gene target
  • Short name
    GSK-2606414 for activation
  • Technique
    activation
  • Alternative name
    GSK-2606414 to measure cellular activation
  • Tissue
    cell
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