GRM2+GRM4 Antibody
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Catalog numberbs-2139R
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PricePlease ask
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Size0.1ml
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Long nameGRM2+GRM4 Primary Polyclonal Antibody
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Also known asGRM2+GRM4 PAb
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CategoryPrimary Antibodies
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ConjugationUnconjugated
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Target AntigenGRM2+GRM4
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SpecificityThis is a highly specific antibody against GRM2+GRM4.
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Modification sNone
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Modification site sUnmodified antibody
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ClonalityPolyclonal antibody
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Clone numberPolyclonal antibody
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Concentration1ug per 1ul
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SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human GRM2+GRM4
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Gene ID number2912
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Tested ApplicationsWB, IHC-P, IF(IHC-P)
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Recommended dilutionsWB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
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Cross reactivityHuman, Mouse, Rat
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Cross reactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
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Background of the target antigenL glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities.
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Purification methodThis antibody was purified via Protein A.
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Storage conditionsKeep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
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Synonym namesNULL
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PropertiesIf you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolGRM2, GRM4
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Short nameAnti-GRM2+GRM4
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TechniqueAntibody, antibodies against human proteins, antibodies for
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HostRabbit (Oryctolagus cuniculus)
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IsotypeImmunoglobulin G (IgG)
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Alternative nameGRM2+GRM4 Polyclonal Antibody
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Alternative techniqueantibodies
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Gene info
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Identity
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Gene
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Long gene nameglutamate metabotropic receptor 2
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Synonyms gene name
- glutamate receptor, metabotropic 2
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Synonyms
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GenBank acession
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Locus
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Discovery year1993-10-21
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Entrez gene record
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Pubmed identfication
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Classification
- Glutamate metabotropic receptors
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameglutamate metabotropic receptor 4
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Synonyms gene name
- glutamate receptor, metabotropic 4
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Synonyms
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GenBank acession
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Locus
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Discovery year1993-10-21
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Entrez gene record
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Pubmed identfication
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Classification
- Glutamate metabotropic receptors
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data