GPCR135 Relaxin 3 Receptor 1 Antibody Conjugated
GPCR135 Relaxin 3 Receptor 1 Antibody Conjugated is available 7 times from Bioss primary conjugated antibodies labs
- CategoryConjugated Primary Antibodies
- Host OrganismRabbit (Oryctolagus cuniculus)
- Target AntigenGPCR135/Relaxin 3 Receptor 1
- SpecificityThis is a highly specific antibody against GPCR135/Relaxin 3 Receptor 1.
- Modification siteNone
- ClonePolyclonal antibody
- Concentration1ug per 1ul
- Subcellular locationExtracellular
- SourceKLH conjugated synthetic peptide derived from human Relaxin 3 Receptor 1
- Gene ID number51289
- CrossreactivityHuman, Mouse, Rat
- Crossreactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
- Antigen backgroundRelaxin Receptor 3 is a G protein-coupled receptor that binds Relaxin 3 and influences differentiation and maintenance of the nervous system. Relaxin Receptor 3 shares sequence similarity with somatostatin receptors and angiotensin receptors. It mediates central processing of sensory signals in the rat and is thought to be a modulator of stress responses. Relaxin Receptor 3 is present in the brain, with highest expression in substantia nigra and pituitary, followed by hippocampus, spinal cord, amygdala, caudate nucleus and corpus callosum, and low level expression in cerebellum. In peripheral tissues there are high levels in adrenal glands and low levels in pancreas, salivery gland, placenta, mammary gland and testis.
- Purification methodThis antibody was purified via Protein A.
- SynonymsRelaxin Receptor 3; G protein coupled receptor GPCR135; G protein coupled receptor SALPR; G-protein coupled receptor SALPR; GPCR SALPR; GPCR 135; GPCR135; Gprotein coupled receptor SALPR; Relaxin 3 receptor 1; Relaxin 3 receptor1; Relaxin 3/INSL7 receptor 1; Relaxin 3/INSL7 receptor1; Relaxin family peptide receptor 3; Relaxin family peptide receptor3; Relaxin/insulin like family peptide receptor 3; Relaxin3 receptor 1; Relaxin3 receptor1; RL3 R1; RL3R 1; RL3R1; RLN3 receptor 1; RLN3 receptor1; RLN3R1; RXFPR3; SALP R; SALPR; somatostatin and angiotensin like peptide receptor; RL3R1_HUMAN.
- Gene target
- Alternative techniqueantibodies
bs-11405R-Biotin | GPCR135/Relaxin 3 Receptor 1 Antibody, Biotin Conjugatedsize: 0.1ml | 408.79 USD
bs-11405R-Cy3 | GPCR135/Relaxin 3 Receptor 1 Antibody, Cy3 Conjugatedsize: 0.1ml | 429.66 USD
bs-11405R-Cy5 | GPCR135/Relaxin 3 Receptor 1 Antibody, Cy5 Conjugatedsize: 0.1ml | 429.66 USD
- Catalog numberbs-11405R-Cy5
- Price429.66 USD
- Long nameGPCR135/Relaxin 3 Receptor 1 Antibody, Cy5 Conjugated
- Tested applicationsIF(IHC-P)
- Recommended dilutionsIF(IHC-P)(1:50-200)
- Storage conditionsKeep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
- Excitation Emission625,650nm/670nm
- PropertiesIf you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor.
- Additional conjugationCy5.5
- DescriptionThe receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
- French translationanticorps
- Short nameGPCR135/Relaxin 3 Receptor 1 Antibody, Conjugated
- TechniqueAntibody, antibodies against human proteins, antibodies for, antibody Conjugates
- Alternative nameGPCR135/Relaxin 3 Receptor 1 (Antibody to), cyanine 5 coupled
1. Gene info
- Long gene namerelaxin/insulin like family peptide receptor 3
- Synonyms gene
- Synonyms gene name
- relaxin 3 receptor 1
- relaxin family peptide receptor 3
- GenBank acession
- Discovery year2004-11-15
- Entrez gene record
- Pubmed identfication
- RefSeq identity
- Relaxin family peptide receptors
- Havana BLAST/BLAT
- ConceptScope note:In vitro method for producing large amounts of specific DNA or RNA fragments of defined length and sequence from small amounts of short oligonucleotide flanking sequences (primers). The essential steps include thermal denaturation of the double-stranded target molecules, annealing of the primers to their complementary sequences, and extension of the annealed primers by enzymatic synthesis with DNA polymerase. The reaction is efficient, specific, and extremely sensitive. Uses for the reaction include disease diagnosis, detection of difficult-to-isolate pathogens, mutation analysis, genetic testing, DNA sequencing, and analyzing evolutionary relationships.
- Tree numbers
- Qualifiersclassification, economics, history, instrumentation, methods, standards, trends, utilization, veterinary, statistics & numerical data, ethics
- PubMedfunctional response to H3 relaxin and other relaxin/insulin peptides of GPCR135 expressed in CHO-K1 cells was measured in the cytosensor microphysiometer and analyzed using inhibitors of signal transduction proteinsanalysis of truncated human relaxin-2 and -3 (H2 and H3) relaxin peptides and their binding and cAMP activities on RXFP1, RXFP2, and RXFP3Results decribe the structural and functional aspects of the interaction between relaxin-3 and its receptor, RXFP3.we demonstrated distinct patterns of signalling for H3 and H2 relaxin and R3(BDelta23-27)R/I5 at the RXFP3 receptorthe negatively charged transmembrane aspartate residue controls activation of the relaxin-3 receptor RXFP3the N-terminus and EL2 domains of RXFP3 and RXFP4 are involved in ligand binding while TM2, 3, and 5 are critical for receptor activation.
- Gene ontology - Biological processpositive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway
- Gene ontology - Cellular component
- Gene ontology - Molecular function
- Entrez Gene
bs-11405R-Cy5.5 | GPCR135/Relaxin 3 Receptor 1 Antibody, Cy5.5 Conjugatedsize: 0.1ml | 429.66 USD
bs-11405R-Cy7 | GPCR135/Relaxin 3 Receptor 1 Antibody, Cy7 Conjugatedsize: 0.1ml | 429.66 USD
bs-11405R-FITC | GPCR135/Relaxin 3 Receptor 1 Antibody, FITC Conjugatedsize: 0.1ml | 408.79 USD
bs-11405R-HRP | GPCR135/Relaxin 3 Receptor 1 Antibody, HRP Conjugatedsize: 0.1ml | 429.66 USD