Goat anti Mouse transferrin
Goat anti Mouse transferrin is available 1 time from Nordc labs
- CategoryPrimary Antibodies
- Antibody is raised inGoat
- Antibody's reacts withMouse
- Antibody's suited forImmunoprecipitation. In immunoelectrophoresis use 2 μl serum or equivalent against 120 μl antiserum. In double radial immunodiffusion use a rosette arrangement with 10 μl antiserum in 3 mm diameter centre well and 2 μl serum samples (neat and serially diluted) in 2 mm diameter peripheral wells. Precipitin titre 1:64 when tested against pooled normal mouse serum in agar-block immunodiffusion titration.
- Protein numbersee ncbi
- Antigen-antibody binding interactionGoat anti Mouse transferrin Antibody
- Antibody come fromPurified transferrin isolated from pooled mouse serum. Freund’s complete adjuvant is used in the first step of the immunization procedure.
- Other descriptionDelipidated, heat inactivated, lyophilized, stable whole antiserum No preservative added. Total protein and IgG concentrations in the antiserum are comparable to those of pooled normal goat serum. No foreign proteins added.
- Long descriptionThe reactivity of the antiserum is restricted to transferrin as tested in immunoelectrophoresis and radial immunodiffusion. A characteristic single precipitin line is obtained with normal serum which shows a reaction of identity with the precipitin line with purified transferrin. In precipitating techniques as immunoelectrophoresis and single and double radial immunodiffusion to identify the presence transferrin in mouse serum or other body fluids and to determine its concentration. This antiserum has not been tested in more sensitive assays as nephelometry, ELISA or use in immunohistology, but this does not exclude such use if proper controls are included.
- Antibody's reacts with these speciesInter-species cross-reactivity is a normal feature of antibodies to Serum proteins, since homologous proteins of different species frequently share antigenic determinants. Crossreactivity of this antiSerum has not been tested in detail.
- Research interestVeterinary
- StorageThe lyophilized antiserum is shipped at ambient temperature and may be stored at +4°C; prolonged storage at or below -20°C. Reconstitute the lyophilized antiserum by adding 1 ml sterile distilled water. Dilutions may be prepared by adding phosphate buffered saline (PBS, pH 7.2). Repeated thawing and freezing should be avoided. If a slight precipitation occurs upon storage, this should be removed by centrifugation. It will not affect the performance of the antiserum. Diluted antiserum should be stored at +4°C, not refrozen, and preferably used the same day. Lyophilized at +4° C--at least 10 years. Reconstituted at or below -20° C--3-5 years. Reconstituted at +4° C--7 days
- Relevant referencesno information yet
- WarningsThis product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals. This datasheet is as accurate as reasonably achievable, but Nordic-MUbio accepts no liability for any inaccuracies or omissions in this information.
- Antibody's specificityPrecipitating polyclonal Goat antiSerum to Mouse transferrin.
- Gene target
- Short nameGoat anti Mouse transferrin
- Techniqueanti mouse, Mouse, anti, Goat
- Alternative namecaprine antibody to Mouse transferrin
- Alternative techniquemurine
GAM/Trf | Goat anti Mouse transferrinsize: 1 mL | 257.05 USD
- Catalog numberGAM/Trf
- Price257.05 USD
- Size1 mL
- DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.This is against a protein of mus musculus directed antibody.
- Latin nameCapra aegagrus hircus,Mus musculus
- TestMouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
0. Gene info
- Long gene nametransferrin
- Discovery year2001-06-22
- Entrez gene record
- Pubmed identfication
- RefSeq identity
- Havana BLAST/BLAT
- ConceptScope note:Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
- Tree numbers
- Qualifiersclassification, economics, history, instrumentation, methods, standards, trends, utilization, veterinary, statistics & numerical data, ethics
- PubMedtransferrin receptor 2 and HFE are involved in holotransferrin-dependent signaling for the regulation of furin which involved Erk phosphorylation. Furin in turn may control hepcidin expression.the value of transferrin receptors (TfRs)/cell reveals a 100-fold increase in the number of TfRs per bEnd3 cells compared to human umbilical vein cells.In conditions of iron overload, hemojuvelin is essential for transferrin-dependent and transferrin-independent hepcidin expression.during later times postinfection (1.5 to 3 h), the virus meets up with transferrin in the Rab11-positive recycling endosomeThese data show that mycobacteria reside in the Rab11(+) endocytic recycling pathway, thereby retaining access to metabolizing transferrin and avoiding endocytosed immunoproteins like Lcn2.Apotransferrin mitigates the neurotoxicity of hemoglobin in a cell culture model of intracerebral hemorrhage.These results indicate that CALM is required for erythroid maturation and transferrin internalization in mice.Together, these data indicate that Lcn2, in combination with transferrin, confines Klebsiella pneumoniae to the airways and prevents invasion into tissue containing the pulmonary vasculature.Transcytosis and brain uptake of transferrin-containing nanoparticles by tuning avidity to transferrin receptor.
- Gene ontology - Biological process
- Gene ontology - Cellular component
- Gene ontology - Molecular function
- Entrez Gene