GDC-H, H protein of glycine decarboxylase complex (GDC)

• Catalog number
  AS05 074
• Price
  Please ask
• Size
  50 µg

• Available ordering format
  Lyophilized in PBS pH 7.4
• Immunogen
  purified GDC-H protein from Spinacia oleracea
• Raised in
  Rabbit
• Clonality
  Polyclonal
• Clone
  Polyclonal
• Purification
  Total IgG
• How to reconstitute
  For reconstitution add 50 µl of sterile water.
• Storage condition
  store lyophilized/reconstituted at -20°C; once reconstituted make aliquots to avoid repeated freeze-thaw cycles. Please, remember to spin tubes briefly prior to opening them to avoid any losses that might occur from lyophilized material adhering to the cap or sides of the tubes.
• Verified applications
  western blot (WB)
• Connected products
  AS06 203A | anti- Idh | isocytrate dehydrogenase rabbit antibody, marker of mitochondrial matrixAS07 212 | anti-VDAC1 marker antibody for mitochondrial outer membranePlant protein extraction buffer Secondary antibodies
• Recommended dilutions for use
  1:5 000 with standard ECL (WB)
• Molecular weight expected аpparent
  16 kDa
• Verified reactivity
  Arabidopsis thaliana, Spinacia oleracea, Triticum aestivum, Vicia faba
• Possible reactivity
  n.a.
• No reactivity
  no confirmed exceptions from predicted reactivity known in the moment
• Supplementary information
  this antibody can be used on total cell extract of Arabidopsis thaliana
• References
  Bancel et al. (2015). Proteomic Approach to Identify Nuclear Proteins in Wheat Grain. J Proteome Res. 2015 Sep 8. Long et al. (2015). Contributions of photosynthetic and non-photosynthetic cell types to leaf respiration in Vicia faba-…L. and their responses to growth temperature. Plant Cell Environ. 2015 Apr 1. doi: 10.1111/pce.12544. Cordoba-Canero et al. (2011). Arabidopsis ARP endonuclease functions in a branched base excision DNA repair pathway completed by LIG1. The Plant J in print
• Scientific context
  The Glycine decarboxylase complex (GDC) is abundant in mitochondria of C3 leaves and functions in photorespiratory carbon recovery. GDC enzyme can account for up to 50% of matrix protein, and is responsible for the most prominent metabolic activity in the mitochondria of illuminated leaves, photorespiration. GDC is a multienzyme complex composed of four component enzymes, the P-, H-, T-, and L-proteins and is responsible for the conversion of glycine produced in the peroxisome to serine in the mitochondria during photorespiratory cycle. The H-protein plays a key role as a mobile substrate that commutes between the other subunits, allowing its lipoic acid -œarm- to visit the active sites of the other three components.
• Notes
  cellular [compartment marker] of mitochondrial matrix
• Protein number
  AT2G35370
• TAIR number
  AT2G35370
• Hyperlink

• Gene target
  GDC-H   protein   glycine   decarboxylase   complex   GDC  
• Gene symbol
  NCAPH, HLA-H, IGHV3-69-1, FUT1, PIGH, NEFH, HFE, RAB11B, ATCAY, RAB35
• Short name
  GDC-H, H protein of glycine decarboxylase complex (GDC)
• Alternative name
  GDC-H, H protein on glycine decarboxylase aggregate (GDC)

Gene info

• Identity
  HGNC:1112
• Gene
  NCAPH
• Long gene name
  non-SMC condensin I complex subunit H
• Synonyms gene
  • BRRN1
• Synonyms gene name
  • barren (Drosophila) homolog
  • barren homolog (Drosophila)
  • barren homolog 1 (Drosophila)
  • non-SMC condensin I complex, subunit H
• Synonyms
  • CAP-H
  • hCAP-H
• GenBank acession
  • BC024211
• Locus
  2q11.2
• Discovery year
  1998-02-11
• Entrez gene record
  23397
• Pubmed identfication
  • 9417923
• RefSeq identity
  • NM_015341
• Classification
  • Condensin I subunits
  • Kleisins
• VEGA ID
  OTTHUMG00000130451

Gene info

• Identity
  HGNC:4965
• Gene
  HLA-H
• Long gene name
  major histocompatibility complex, class I, H (pseudogene)
• GenBank acession
  • M31944
• Locus
  6p22.1
• Discovery year
  1991-08-01
• Entrez gene record
  3136
• Pubmed identfication
  • 1517564
  • 2294403
• RefSeq identity
  • NR_001434
• Classification
  • Histocompatibility complex
• VEGA ID
  OTTHUMG00000031160
• Locus Specific Databases
  • IMGT/HLA Database

Gene info

• Identity
  HGNC:5631
• Gene
  IGHV3-69-1
• Long gene name
  immunoglobulin heavy variable 3-69-1 (pseudogene)
• Synonyms gene
  • IGHV3-H
• Synonyms gene name
  • immunoglobulin heavy variable 3-H (provisional)
  • immunoglobulin heavy variable 3-H pseudogene (provisional)
  • immunoglobulin heavy variable 3-H (pseudogene)
• Synonyms
  • IGHV3-h
• GenBank acession
  • AJ879484
• Locus
  14q32.33
• Discovery year
  2000-04-04
• Entrez gene record
  28402
• Pubmed identfication
  • 16133446
• Classification
  • Immunoglobulin heavy locus at 14q32.33
• VEGA ID
  OTTHUMG00000191145

Gene info

• Identity
  HGNC:4012
• Gene
  FUT1
• Long gene name
  fucosyltransferase 1 (H blood group)
• Synonyms gene
  • H
  • HSC
• Synonyms gene name
  • fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, Bombay phenotype included)
  • fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase)
• Synonyms name
  • galactoside 2-alpha-L-fucosyltransferase
• Locus
  19q13.33
• Discovery year
  1989-06-06
• Entrez gene record
  2523
• RefSeq identity
  • NM_000148
• Classification
  • Fucosyltransferases
  • Blood group antigens
• VEGA ID
  OTTHUMG00000183325
• Locus Specific Databases
  • Blood Group Antigen Mutation Database
  • LRG_810

Gene info

• Identity
  HGNC:8964
• Gene
  PIGH
• Long gene name
  phosphatidylinositol glycan anchor biosynthesis class H
• Synonyms gene name
  • phosphatidylinositol glycan, class H
• Synonyms
  • GPI-H
• Synonyms name
  • phosphatidylinositol N-acetylglucosaminyltransferase subunit
• Locus
  14q24.1
• Discovery year
  1994-09-06
• Entrez gene record
  5283
• Pubmed identfication
  • 8204896
• RefSeq identity
  • NM_004569
• Classification
  • Phosphatidylinositol glycan anchor biosynthesis
• VEGA ID
  OTTHUMG00000171806

Gene info

• Identity
  HGNC:7737
• Gene
  NEFH
• Long gene name
  neurofilament heavy chain
• Synonyms gene name
  • neurofilament, heavy polypeptide 200kDa
  • neurofilament heavy polypeptide
  • neurofilament heavy
• Synonyms
  • NF-H
  • NFH
• Locus
  22q12.2
• Discovery year
  1988-08-31
• Entrez gene record
  4744
• RefSeq identity
  • NM_021076
• Classification
  • Intermediate filaments Type IV
• VEGA ID
  OTTHUMG00000151155
• Locus Specific Databases
  • ALSOD, the Amyotrophic Lateral Sclerosis Online Genetic Database

Gene info

• Identity
  HGNC:4886
• Gene
  HFE
• Long gene name
  homeostatic iron regulator
• Synonyms gene name
  • hemochromatosis
• Synonyms
  • HLA-H
  • HFE1
• Synonyms name
  • high Fe
• Locus
  6p22.2
• Discovery year
  1986-01-01
• Entrez gene record
  3077
• Pubmed identfication
  • 3460331
  • 28474781
  • 9054933
• Classification
  • C1-set domain containing
• VEGA ID
  OTTHUMG00000016348
• Locus Specific Databases
  • ALSOD, the Amyotrophic Lateral Sclerosis Online Genetic Database
  • LRG_748

Gene info

• Identity
  HGNC:9761
• Gene
  RAB11B
• Long gene name
  RAB11B, member RAS oncogene family
• Synonyms
  • H-YPT3
• GenBank acession
  • X79780
• Locus
  19p13.2
• Discovery year
  1999-02-23
• Entrez gene record
  9230
• Pubmed identfication
  • 7811277
• RefSeq identity
  • NM_004218
• Classification
  • RAB, member RAS oncogene GTPases
• VEGA ID
  OTTHUMG00000182278

Gene info

• Identity
  HGNC:779
• Gene
  ATCAY
• Long gene name
  ATCAY kinesin light chain interacting caytaxin
• Synonyms gene name
  • ataxia, cerebellar, Cayman type
  • ATCAY, caytaxin
• Synonyms
  • BNIP-H
• Synonyms name
  • Cayman ataxia
  • caytaxin
• Locus
  19p13.3
• Discovery year
  1997-01-10
• Entrez gene record
  85300
• Pubmed identfication
  • 8845847
  • 14556008
• Classification
  • BCH domain containing
• VEGA ID
  OTTHUMG00000181836

Gene info

• Identity
  HGNC:9774
• Gene
  RAB35
• Long gene name
  RAB35, member RAS oncogene family
• Synonyms
  • H-ray
• GenBank acession
  • X79781
• Locus
  12q24.23
• Discovery year
  1999-09-29
• Entrez gene record
  11021
• Classification
  • RAB, member RAS oncogene GTPases
• VEGA ID
  OTTHUMG00000169159

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