Glutamyl Endopeptidase Staphylococcus aureus (Native Protein)

• Catalog number
  32 100 203
• Price
  Please ask
• Size
  100 µg

• Protein type
  Native
• Protein subtype
  EC 3.4.21.19
• Protein family
  Bacterial Serine protease
• Protein description
  Preferentially cleaves peptide bonds on the carboxyl-terminal side of aspartate and glutamate. Along with other extracellular proteases it is involved in colonization and infection of human tissues. Required for proteolytic maturation of thiol protease SspB and inactivation of SspC, an inhibitor of SspB. It is the most important protease for degradation of fibronectin-binding protein (FnBP) and surface protein A, which are involved in adherence to host cells. May also protect bacteria against host defense mechanism by cleaving the immunoglobulin classes IgG, IgA and IgM. May be involved in the stability of secreted lipases.
• Research area interests
  N/A
• Package form
  liquid
• Tested applications
  Screening of inhibitors for Glutamyl Endopeptidase; Characterization of structure and function;
• Other names
  Staphylococcal serine proteinase, Endoproteinase Glu-C
• Peptide sequence
  MKGKFLKVSSLFVATLTTATLVSSPAANALSSKAMDNHPQQTQSSKQQTPKIQKGGNLKPLEQREHANVILPNNDRHQITDTTNGHYAPVTYIQVEAPTGTFIASGVVVGKDTLLTNKHVVDATHGDPHALKAFPSAINQDNYPNGGFTAEQITKYSGEGDLAIVKFSPNEQNKHIGEVVKPATMSNNAETQVNQNITVTGYPGDKPVATMWESKGKITYLKGEAMQYDLSTTGGNSGSPVFNEKNEVIGIHWGGVPNEFNGAVFINENVRNFLKQNIEDIHFANDDQPNNPDNPDNPNNPDNPNNPDEPNNPDNPNNPDNPDNGDNNNSDNPDAA
• Available target modification
  No
• Expression system
  Staphylococcus aureus V8
• Product Subtype
  full length
• Active form
  Yes
• Tag
  untagged
• Contents
  20 mM Tris-HCl pH 7.8, 5 mM CaCl2
• Protein purity
  >95%
• Molecular weight
  30 kDa
• UniProt number
  P0C1U8
• Gene number
  3920389
• Abbreviation
  SAOUHSC_00988
• Full name
  glutamyl endopeptidase
• Other desciption
  Glutamyl endopeptidase (EC 3.4.21.19, synonyms: V8 proteinase, serine protease V8, endoproteinase Glu-C) is purified from Staphylococcus aureus V8.
• Purification
  Mentioned in the data sheet
• PubMed citations
  See the data sheet
• Warnings
  For Research Use only.
• Shipping conditions
  dry ice
• Storage condition
  Store at -70°C
• Technical datasheet
  Contact us to receive the datasheet
• Representative figure
• Other products

• Gene target
  Glutamyl   Endopeptidase   Staphylococcus   aureus   Native   Protein  
• Short name
  Glutamyl Endopeptidase Staphylococcus aureus (Native Protein)
• Species
  Staphylococcus aureus subsp. aureus NCTC 8325 (strain: NCTC 8325, sub-species: aureus)
• Alternative name
  Glutamyl Endopeptidase Staphylococcus aureus (Native Protein)

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