GEF H1 (Ser886) Antibody, HRP Conjugated

• Catalog number
  bs-2201R-HRP
• Price
  Please ask
• Size
  0.1ml

• Long name
  GEF H1 (Ser886) Polyclonal Antibody, HRP Conjugated
• Category
  Conjugated Primary Antibodies
• Conjugation
  HRP
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  GEF H1 Ser886
• Specificity
  This is a highly specific antibody against GEF H1 Ser886.
• Modification
  Phosphorylation
• Modification site
  Ser886
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  KLH conjugated synthetic phosphopeptide derived from human Arhgef2 around the phosphorylation site of Ser886
• Gene ID number
  9181
• Tested applications
  WB, IHC-P
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500)
• Crossreactivity
  Human, Mouse, Rat
• Crossreactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Antigen background
  GEF-H1 is a Rho guanine nucleotide exchange factor that localizes to microtubules and regulates Rho activity in response to microtubule destabilization (loss of interaction between GEF-H1 and microtubules leads to activation of Rho). This protein has also been shown to localize to tight junctions and modulate polarized cell permeability.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% Gentamicin. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
• Excitation Emission
  N/A
• Synonyms
  GEF H1phospho S886; Arhgef2Ser886; Lbcl1; Lfc; mKIAA0651; AA408978; ARHG2; ARHGEF 2; ARHGEF-2; ARHGEF2; GEF; GEF H1; GEF-H1; GEFH1; LFP40; MGC95068; P40; Prolerating cell nucleolar antigen p40; Protein GEF-H1; rho/rac guanine nucleotide exchange factor GEF 2; rho/rac guanine nucleotide exchange factor 2; rho/rac guanine nucleotide exchange factor.
• Properties
  If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. HRP conjugates are often primary rabbit polyclonal antibodies couples to the enzyme horseradish peroxidase (HRP), found in the roots of horseradish. Also monoclonal HRP conjugates are often used for Western Blot.
• Additional conjugation
  HRP Conjugated
• French translation
  anticorps

• Gene target
  GEF   Ser886   Conjugated  
• Gene symbol
  RAPGEF5, RAPGEF6, ARHGEF2, RAPGEF2, SLC2A4RG
• Short name
  Anti-GEF H1 Ser886
• Technique
  Antibody, antibodies against human proteins, antibodies for, antibody Conjugates
• Isotype
  Immunoglobulin G (IgG)
• Label
  HRP
• Alternative name
  Anti-GEF H1 Ser886 PAb HRP
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:16862
• Gene
  RAPGEF5
• Long gene name
  Rap guanine nucleotide exchange factor 5
• Synonyms gene name
  • Rap guanine nucleotide exchange factor (GEF) 5
• Synonyms
  • KIAA0277
  • GFR
  • MR-GEF
• Synonyms name
  • M-Ras-regulated GEF
• GenBank acession
  • D87467
• Locus
  7p15.3
• Discovery year
  2004-03-01
• Entrez gene record
  9771
• Pubmed identfication
  • 9039502
  • 10486569
• RefSeq identity
  • NM_012294
• VEGA ID
  OTTHUMG00000152525

Gene info

• Identity
  HGNC:20655
• Gene
  RAPGEF6
• Long gene name
  Rap guanine nucleotide exchange factor 6
• Synonyms gene
  • PDZGEF2
• Synonyms gene name
  • PDZ domain containing guanine nucleotide exchange factor (GEF) 2
  • Rap guanine nucleotide exchange factor (GEF) 6
• Synonyms
  • RA-GEF-2
  • PDZ-GEF2
• GenBank acession
  • AF117947
• Locus
  5q31.1
• Discovery year
  2003-09-03
• Entrez gene record
  51735
• Pubmed identfication
  • 11524421
  • 12095257
• RefSeq identity
  • NM_016340
• Classification
  • PDZ domain containing
• VEGA ID
  OTTHUMG00000162683

Gene info

• Identity
  HGNC:682
• Gene
  ARHGEF2
• Long gene name
  Rho/Rac guanine nucleotide exchange factor 2
• Synonyms gene name
  • rho/rac guanine nucleotide exchange factor (GEF) 2
  • Rho/Rac guanine nucleotide exchange factor (GEF) 2
• Synonyms
  • LFP40
  • GEF-H1
  • KIAA0651
  • P40
  • Lfc
  • GEFH1
• GenBank acession
  • AB014551
• Locus
  1q22
• Discovery year
  2000-06-09
• Entrez gene record
  9181
• Pubmed identfication
  • 9857026
  • 9734811
• RefSeq identity
  • NM_004723
• Classification
  • Dbl family Rho GEFs
  • Pleckstrin homology domain containing
  • MicroRNA protein coding host genes
• VEGA ID
  OTTHUMG00000017464

Gene info

• Identity
  HGNC:16854
• Gene
  RAPGEF2
• Long gene name
  Rap guanine nucleotide exchange factor 2
• Synonyms gene
  • PDZGEF1
• Synonyms gene name
  • PDZ domain containing guanine nucleotide exchange factor (GEF) 1
  • Rap guanine nucleotide exchange factor (GEF) 2
• Synonyms
  • PDZ-GEF1
  • RA-GEF
  • DKFZP586O1422
  • KIAA0313
• Synonyms name
  • Rap GEP
• GenBank acession
  • AB002311
• Locus
  4q32.1
• Discovery year
  2003-05-20
• Entrez gene record
  9693
• Pubmed identfication
  • 9205841
  • 10934204
• RefSeq identity
  • NM_014247
• Classification
  • MicroRNA protein coding host genes
  • PDZ domain containing
• VEGA ID
  OTTHUMG00000161451

Gene info

• Identity
  HGNC:15930
• Gene
  SLC2A4RG
• Long gene name
  SLC2A4 regulator
• Synonyms
  • GEF
  • HDBP1
  • Si-1-2
  • Si-1-2-19
• Synonyms name
  • GLUT4 enhancer factor
  • Huntington's disease gene regulatory region-binding protein 1
• GenBank acession
  • AF249267
• Locus
  20q13.33
• Discovery year
  2001-06-21
• Entrez gene record
  56731
• Pubmed identfication
  • 10825161
• RefSeq identity
  • NM_020062
• VEGA ID
  OTTHUMG00000032997

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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