GCOM1 Antibody

• Catalog number
  bs-8403R
• Price
  Please ask
• Size
  0.1ml

• Long name
  GCOM1 Primary Polyclonal Antibody
• Also known as
  GCOM1 PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  GCOM1
• Specificity
  This is a highly specific antibody against GCOM1.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human GCOM1
• Gene ID number
  145781
• Tested Applications
  WB, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  Glutamate receptors mediate most excitatory neurotransmission in the brain and play an important role in neural plasticity, neural development and neurodegeneration. Ionotropic glutamate receptors are categorized into NMDA receptors and kainate/AMPA receptors, both of which contain glutamate-gated, cation-specific ion channels. Synaptic and extrasynaptic NMDA receptors have been shown to have opposite effects on neuronal survival, CREB function and gene regulation. Gcom1 (GRINL1A complex locus protein 1), also known as GUP (GRINL1A upstream protein) and Gcom (GRINL1A combined protein), is a 466 amino acid protein that is a component of the GRINL1A complex transcription unit, which is thought to be involved in the modulation of glutamatergic neurotransmission through interaction with the NR1 subunit of the NMDA receptor. Gcom1 is expressed in small intestine, lung, liver, heart, skeletal muscle, testis and prostate and also colocalizes with NR1 in cortical and hippocampal neurons. There are eleven isoforms of Gcom1 that are produced as a result of alternative splicing events.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  Gcom2; Glutamate receptor ionotropic N methyl D aspartate like 1A combined; GRINL1A; GRINL1A combined protein; GRINL1A combined protein Gcom12; GRINL1A upstream protein; Gup1; Gup2; NMDAR1 subunit interacting protein.
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  GCOM1  
• Gene symbol
  MYZAP, GCOM1
• Short name
  Anti-GCOM1
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  GCOM1 Polyclonal Antibody
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:43444
• Gene
  MYZAP
• Long gene name
  myocardial zonula adherens protein
• Synonyms
  • MYOZAP
  • Gup
  • Gup1
  • GCOM1
• Synonyms name
  • myocardium-enriched zonula adherens protein
• GenBank acession
  • FJ970029
• Locus
  15q21.3
• Discovery year
  2011-11-03
• Entrez gene record
  100820829
• Pubmed identfication
  • 20093627
  • 21992629
  • 22160502
• RefSeq identity
  • NM_001018100
• VEGA ID
  OTTHUMG00000132453

Gene info

• Identity
  HGNC:26424
• Gene
  GCOM1
• Long gene name
  GCOM1, MYZAP-POLR2M combined locus
• Synonyms gene name
  • GRINL1A complex locus 1
• Synonyms
  • FLJ30973
  • GRINL1A
  • MYZAP-POLR2M
• Synonyms name
  • MYZAP-POLR2M readthrough
• Locus
  15q21.3
• Discovery year
  2008-08-05
• Entrez gene record
  145781
• Pubmed identfication
  • 15233991
  • 18849881
• RefSeq identity
  • NM_001018090
• VEGA ID
  OTTHUMG00000176411

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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