APC-Linked Polyclonal Antibody to Glutamate Cysteine Ligase, Modifier Subunit (GCLM)

• Catalog number
  MBS2050831
• Price
  Please ask
• Size
  0,1 mg

• Other size
  please contact us to order other different size
• Properties
  If you buy Antibodies supplied by MyBioSource they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Gene
  Cys or cysteines ChEMBL54943
• Group
  Polyclonals and antibodies
• About
  Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.
• French translation
  anticorps

• Gene target
  APC-Linked   Glutamate   Cysteine   Ligase   Modifier   Subunit   GCLM  
• Gene symbol
  APC, GCLM
• Short name
  APC-Linked Polyclonal Antibody Glutamate Cysteine Ligase, Modifier Subunit (GCLM)
• Technique
  Polyclonal, Antibody, antibodies against human proteins, antibodies for, Polyclonal antibodies (pAbs) are mostly rabbit or goat antibodies that are secreted by different B cells, whereas monoclonal antibodies come from a single N cell lineage. Pabs are a collection of immunoglobulin molecules that react against a specific antigen, each identifying a different epitope.
• Label
  APC
• Alternative name
  adenomatous polyposis coli-Linked polyclonal (antibody to-) to Glutamate Cysteine Ligase, Modifier functionnal sequence (glutamate-cysteine ligase, modifier subunit)
• Alternative technique
  polyclonals, antibodies
• Alternative to gene target
  adenomatous polyposis coli, BTPS2 and DP2 and DP2.5 and DP3 and GS and PPP1R46, APC and IDBG-37007 and ENSG00000134982 and 324, microtubule plus-end binding, nuclei, Apc and IDBG-134573 and ENSMUSG00000005871 and 11789, BT.25770 and IDBG-644937 and ENSBTAG00000018852 and 533233

Gene info

• Identity
  HGNC:583
• Gene
  APC
• Long gene name
  APC regulator of WNT signaling pathway
• Synonyms gene name
  • adenomatosis polyposis coli
  • adenomatous polyposis coli
  • APC, WNT signaling pathway regulator
• Synonyms
  • DP2
  • DP3
  • DP2.5
  • PPP1R46
• Synonyms name
  • protein phosphatase 1, regulatory subunit 46
• GenBank acession
  • M74088
• Locus
  5q22.2
• Discovery year
  1986-01-01
• Entrez gene record
  324
• Pubmed identfication
  • 1651563
• RefSeq identity
  • NM_000038
• Classification
  • Protein phosphatase 1 regulatory subunits
  • Armadillo repeat containing
• VEGA ID
  OTTHUMG00000128806
• Locus Specific Databases
  • Adenomatous polyposis coli mutation database
  • UMD Locus Specific Databases
  • Global Variome shared LOVD
  • APC database at LOVD-China
  • LOVD - Leiden Open Variation Database
  • LRG_130

Gene info

• Identity
  HGNC:4312
• Gene
  GCLM
• Long gene name
  glutamate-cysteine ligase modifier subunit
• Synonyms gene
  • GLCLR
• Synonyms gene name
  • glutamate-cysteine ligase, modifier subunit
• Synonyms name
  • gamma-glutamylcysteine synthetase
• GenBank acession
  • L35546
• Locus
  1p22.1
• Discovery year
  1995-01-30
• Entrez gene record
  2730
• Pubmed identfication
  • 7826375
• RefSeq identity
  • NM_002061
• VEGA ID
  OTTHUMG00000010562

MeSH Data

• Name
  Ligase Chain Reaction
• Concept
  Scope note: A DNA amplification technique based upon the ligation of OLIGONUCLEOTIDE PROBES. The probes are designed to exactly match two adjacent sequences of a specific target DNA. The chain reaction is repeated in three steps in the presence of excess probe: (1) heat denaturation of double-stranded DNA, (2) annealing of probes to target DNA, and (3) joining of the probes by thermostable DNA ligase. After the reaction is repeated for 20-30 cycles the production of ligated probe is measured.
• Tree numbers
  • E05.393.620.311
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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