Gastrin receptor/CCKBR Antibody, ALEXA FLUOR 555
-
Catalog numberbs-1777R-A555
-
PricePlease ask
-
Size100ul
-
-
Long nameGastrin receptor/CCKBR Antibody, ALEXA FLUOR 555 Conjugated
-
Also known asAnti-Gastrin receptor/GASR/CCKBR PAb ALEXA FLUOR 555
-
CategoryConjugated Primary Antibodies
-
Conjugated withALEXA FLUOR® 555
-
Host OrganismRabbit (Oryctolagus cuniculus)
-
Target AntigenGastrin receptor/GASR/CCKBR
-
SpecificityThis is a highly specific antibody against Gastrin receptor/GASR/CCKBR.
-
ModificationUnmodified
-
Modification SiteNone
-
ClonalityPolyclonal
-
ClonePolyclonal antibody
-
Concentration1ug per 1ul
-
Immunogen range300-350/447
-
Subcellular locationCytoplasm
-
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Gastrin receptor
-
Gene ID Number887
-
Swiss ProtP32239
-
Tested applicationsIF(IHC-P)
-
Recommended dilutionsIF(IHC-P)(1:50-200)
-
CrossreactivityHuman, Mouse, Rat
-
Cross reactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
-
Background of the antigenReceptor for gastrin and cholecystokinin. The CKK-B receptors occur throughout the central nervous system where they modulate anxiety, analgesia, arousal, and neuroleptic activity. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Isoform 2 is constitutively activated and may regulate cancer cell proliferation via a gastrin-independent mechanism.
-
PurificationPurified by Protein A.
-
Storage conditionsStore this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
-
Excitation emission553nm/568nm
-
SynonymsGASR; CCK-B; CCK2R; Gastrin/cholecystokinin type B receptor; CCK-B receptor; CCK-BR; Cholecystokinin-2 receptor; CCK2-R; CCKBR; CCKRB
-
PropertiesFor facs or microscopy Alexa 1 conjugate. Very high photo stable ALEXA conjugate. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
-
ConjugationAlexa Fluor, ALEXA FLUOR 555
-
DescriptionThe receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
-
French translationanticorps
-
Gene target
-
Gene symbolCCKBR
-
Short nameAnti-Gastrin receptor/GASR/CCKBR
-
TechniqueAntibody, antibodies against human proteins, antibodies for
-
IsotypeImmunoglobulin G (IgG)
-
LabelALEXA FLUOR 555
-
Alternative nameGastrin receptor/CCKBR Antibody, ALEXA FLUOR 555
-
Alternative techniqueantibodies
-
Alternative to gene targetcholecystokinin B receptor, CCK-B and CCK2R and GASR, CCKBR and IDBG-28586 and ENSG00000110148 and 887, 1-phosphatidylinositol-3-kinase regulator activity, Plasma membranes, Cckbr and IDBG-204676 and ENSMUSG00000030898 and 12426, CCKBR and IDBG-634214 and ENSBTAG00000005236 and 281665
-
Gene info
-
Identity
-
Gene
-
Long gene namecholecystokinin B receptor
-
GenBank acession
-
Locus
-
Discovery year1993-07-13
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- Cholecystokinin receptors
-
VEGA ID
MeSH Data
-
Name
-
ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
-
Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
-
Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data