Gastrin receptor/CCKBR Antibody
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Catalog number
bs-1777R
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Price
Please ask
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Size
0.1ml
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Long name
Gastrin receptor/CCKBR Antibody
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Also known as
Gastrin receptor/CCKBR Antibody
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Category
Primary Antibodies
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Conjugation
Unconjugated
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Target Antigen
Gastrin receptor/GASR/CCKBR
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Specificity
This is a highly specific antibody against Gastrin receptor/GASR/CCKBR.
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Modification s
None
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Modification site s
Unmodified antibody
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Clonality
Polyclonal antibody
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Clone number
Polyclonal antibody
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Concentration
1ug per 1ul
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Immunogen range
300-350/447
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Subcellular location
Cytoplasm
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Source
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Gastrin receptor
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Gene ID number
887
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Swiss Prot
P32239
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Tested Applications
WB, IHC-P, IF(IHC-P)
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Recommended dilutions
WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
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Cross reactivity
Human, Mouse, Rat
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Cross reactive species details
Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
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Background of the target antigen
Receptor for gastrin and cholecystokinin. The CKK-B receptors occur throughout the central nervous system where they modulate anxiety, analgesia, arousal, and neuroleptic activity. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Isoform 2 is constitutively activated and may regulate cancer cell proliferation via a gastrin-independent mechanism.
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Purification method
This antibody was purified via Protein A.
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Storage conditions
Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
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Synonym names
GASR; CCK-B; CCK2R; Gastrin/cholecystokinin type B receptor; CCK-B receptor; CCK-BR; Cholecystokinin-2 receptor; CCK2-R; CCKBR; CCKRB
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Properties
If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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Description
The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
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French translation
anticorps
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Gene target
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Gene symbol
CCKBR
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Short name
Anti-Gastrin receptor/GASR/CCKBR
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Technique
Antibody, antibodies against human proteins, antibodies for
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Host
Rabbit (Oryctolagus cuniculus)
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Isotype
Immunoglobulin G (IgG)
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Alternative name
Gastrin receptor/CCKBR Antibody
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Alternative technique
antibodies
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Alternative to gene target
cholecystokinin B receptor, CCK-B and CCK2R and GASR, CCKBR and IDBG-28586 and ENSG00000110148 and 887, 1-phosphatidylinositol-3-kinase regulator activity, Plasma membranes, Cckbr and IDBG-204676 and ENSMUSG00000030898 and 12426, CCKBR and IDBG-634214 and ENSBTAG00000005236 and 281665
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Gene info
MeSH Data
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Name
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Concept
Scope note:
Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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